Challenges for the development of vaccines against Haemophilus influenzae and Neisseria meningitidis [PDF]
The development of protein–polysaccharide conjugate vaccines has had a major impact on Haemophilus influenzae type b disease. The application of this technology to Neisseria meningitidis is also striking, particularly for serogroup C.
Kyd, Jennelle M. +2 more
core +3 more sources
The authors studied the results of immunization among the children against the infection caused by haemophilus influenzae type B by two vaccines: ACT HIB and Hiberix.
V.V. Botvin’eva +3 more
doaj +2 more sources
Recommended immunization schedule for children and adolescents: Immunization Guideline (8th edition) released by the Korean Pediatric Society in 2015 [PDF]
This report includes the recommended immunization schedule table for children and adolescents based on the 8th (2015) and revised 7th (2012) Immunization Guidelines released by the Committee on Infectious Diseases of the Korean Pediatric Society (KPS ...
Jong-Hyun Kim +11 more
doaj +1 more source
Conjugate Vaccines and the Carriage of Haemophilus influenzae Type b
Pharyngeal carriage of Haemophilus influenzae type b (Hib) is important in the transmission of Hib organisms, the pathogenesis of Hib disease, and the development of immunity to the bacterium.
Marina L. Barbour, D. Phil
doaj +1 more source
Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch +6 more
wiley +1 more source
Conjugate vaccines have reduced the incidence of invasive disease caused by Haemophilus influenzae, type b (Hib), in industrialized countries and may be highly effective against Streptococcus pneumoniae.
Marc Lipsitch
doaj +1 more source
USE OF HAEMOPHILUS VACCINE IN CONNECTICUT [PDF]
Although the vaccine against Haemophilus influenzae type b (Hib) is recommended for all children 24-60 months of age and high risk children 18-23 months of age, there is little information about the extent to which these recommendations have been implimented. To assess the use of the vaccine we randomly selected from the hospital logs 202 (2.5%) of the
Eugene D Shapiro +4 more
openaire +1 more source
Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian +5 more
wiley +1 more source
Planning for new health interventions for developing countries : an integrated strategy to prepare for malaria vaccines and lessons for future interventions [PDF]
Historically, new health interventions have been developed primarily to address the needs of the wealthy in developed countries. Where drugs, vaccines, diagnostic tests and other interventions happened to address diseases prevalent in the developing ...
Brooks, Alan
core +1 more source
Conjugate Haemophilus influenzae type b vaccines for sickle cell disease. [PDF]
BACKGROUND: People affected with sickle cell disease are at high risk of infection from Haemophilus influenzae type b. Before the implementation of Haemophilus influenzae type b conjugate vaccination in high-income countries, this was responsible for a ...
Chalumeau, Martin +4 more
core +1 more source

