Results 111 to 120 of about 1,818,643 (411)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

A systematic review and meta-analysis of systematic and topical tranexamic acid administration in aesthetic plastic surgery

open access: yesPerioperative Medicine
Introduction Tranexamic acid has been widely used in plastic surgery. However, its efficacy has yet to be fully established. This meta-analysis aimed to determine its effectiveness in aesthetic plastic surgery.
Jerzy Kolasiński   +4 more
doaj   +1 more source

Computer-Generated Photorealistic Hair [PDF]

open access: yesarXiv, 2002
This paper presents an efficient method for generating and rendering photorealistic hair in two dimensional pictures. The method consists of three major steps. Simulating an artist drawing is used to design the rough hair shape. A convolution based filter is then used to generate photorealistic hair patches.
arxiv  

Automatic Animation of Hair Blowing in Still Portrait Photos [PDF]

open access: yesarXiv, 2023
We propose a novel approach to animate human hair in a still portrait photo. Existing work has largely studied the animation of fluid elements such as water and fire. However, hair animation for a real image remains underexplored, which is a challenging problem, due to the high complexity of hair structure and dynamics.
arxiv  

The Currency of White Women\u27s Hair in a Down Economy [PDF]

open access: yes, 2010
This short essay is a reflection on the relationship between the economy and women’s hair. I suggest that examining women’s spending on hair care products during uncertain financial conditions provides insight into the gendered aspects of the economy. As
Crawford, Bridget J.
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Realistic Hair Simulation Using Image Blending [PDF]

open access: yesarXiv, 2019
In this presented work, we propose a realistic hair simulator using image blending for dermoscopic images. This hair simulator can be used for benchmarking and validation of the hair removal methods and in data augmentation for improving computer aided diagnostic tools.
arxiv  

Hair-on-End [PDF]

open access: yesThe American Society of Tropical Medicine and Hygiene, 2013
A 25-year-old man was admitted with a long history of weakness and wasting. In fact, he said he “was born—and fell ill.” He claimed to be still unmarried as a result of his illness. One year earlier he had been admitted with pain in his left hip. Despite several hospital admissions, an explanation for his illness had not been found.
Klaas Koop   +2 more
openaire   +3 more sources

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

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