Back to the Future: From Appendage Development Toward Future Human Hair Follicle Neogenesis
Hair disorders such as alopecia and hirsutism often impact the social and psychological well-being of an individual. This also holds true for patients with severe burns who have lost their hair follicles (HFs).
Simon C. de Groot+4 more
doaj +1 more source
Calcium entry into stereocilia drives adaptation of the mechanoelectrical transducer current of mammalian cochlear hair cells [PDF]
Mechanotransduction in the auditory and vestibular systems depends on mechanosensitive ion channels in the stereociliary bundles that project from the apical surface of the sensory hair cells.
Corns, Laura F+3 more
core +2 more sources
Background Geriatric patients are affected by a range of skin conditions and dermatological diseases, functional limitations and chronic diseases. Skin problems are highly prevalent in elderly populations.
Elisabeth Hahnel+3 more
doaj +1 more source
Aminoglycoside-Induced Phosphatidylserine Externalization in Sensory Hair Cells Is Regionally Restricted, Rapid, and Reversible [PDF]
The aminophospholipid phosphatidylserine (PS) is normally restricted to the inner leaflet of the plasma membrane. During certain cellular processes, including apoptosis, PS translocates to the outer leaflet and can be labeled with externally applied ...
Gale, Jonathan E+4 more
core +1 more source
Generation of inner ear organoids with functional hair cells from human pluripotent stem cells
The derivation of human inner ear tissue from pluripotent stem cells would enable in vitro screening of drug candidates for the treatment of hearing and balance dysfunction and may provide a source of cells for cell-based therapies of the inner ear. Here
Karl R. Koehler+6 more
semanticscholar +1 more source
Lifetime of unstable hairy black holes [PDF]
During the last two decades solutions of black holes with various types of "hair" have been discovered. Remarkably, it has been established that many of these hairy black holes are unstable-- under small perturbations the hair may collapse. While the static sector of theories admitting hair is well explored by now, our picture of the dynamical process ...
arxiv +1 more source
Solar ultraviolet protection provided by human head hair [PDF]
The solar erythemal UV irradiances through human hair and the protection from UV provided by human head hair have been investigated for a solar zenith angle (SZA) range of 17 to 51 degrees for the conditions of a head upright in full sun, a head upright ...
Allen+16 more
core +2 more sources
Lactate dehydrogenase activity drives hair follicle stem cell activation
Although normally dormant, hair follicle stem cells (HFSCs) quickly become activated to divide during a new hair cycle. The quiescence of HFSCs is known to be regulated by a number of intrinsic and extrinsic mechanisms.
A. Flores+16 more
semanticscholar +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
NeuralHDHair: Automatic High-fidelity Hair Modeling from a Single Image Using Implicit Neural Representations [PDF]
Undoubtedly, high-fidelity 3D hair plays an indispensable role in digital humans. However, existing monocular hair modeling methods are either tricky to deploy in digital systems (e.g., due to their dependence on complex user interactions or large databases) or can produce only a coarse geometry.
arxiv