Results 151 to 160 of about 11,068,075 (352)
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.Islatravir‐loaded dissolving microarray patches (MAPs) provide a minimally invasive, long‐acting solution for HIV‐1 prevention and treatment. In rats, sustained islatravir delivery lasts up to three months, while in minipigs, efficacious plasma levels are detected for six days.
Qonita Kurnia Anjani +11 more
wiley +1 more source
PCP and Wnt pathway components act in parallel during zebrafish mechanosensory hair cell orientation
Nature Communications, 2019 Planar cell polarity (PCP) regulates hair cell orientation in the zebrafish lateral line. Here, the authors show that mutating Wnt pathway genes (wnt11f1, fzd7a/b, and gpc4) causes concentric hair cell patterns not regulated by PCP, thus showing PCP/Wnt ...
Joaquin Navajas Acedo +7 more
doaj +1 more source
Activation of CHK1 in Supporting Cells Indirectly Promotes Hair Cell Survival
Frontiers in Cellular Neuroscience, 2017 The sensory hair cells of the inner ear are exquisitely sensitive to ototoxic insults. Loss of hair cells after exposure to ototoxic agents causes hearing loss. Chemotherapeutic agents such as cisplatin causes hair cell loss.
Azadeh Jadali +5 more
doaj +1 more source
A STUDY OF THE ORIENTATION OF THE SENSORY HAIRS OF THE RECEPTOR CELLS IN THE LATERAL LINE ORGAN OF FISH, WITH SPECIAL REFERENCE TO THE FUNCTION OF THE RECEPTORS [PDF]
, 1962 Åke Flock, Jan Wersäll
openalex +1 more source
Advanced Healthcare Materials, EarlyView.This study presents a novel implantable drug delivery systemwith a biodegradable poly(caprolactone) membrane and compressed drug core forsustained release. These implantable devices deliver risperidone in vitro for 170 days and in vivo for 49 days in rats, showing promise for chronic conditions like schizophrenia.
Linlin Li +9 more
wiley +1 more source
Amplitude death state for hearing [PDF]
arXiv, 2012 We propose amplitude death phenomenon as an underlying mechanism of auditory transduction. When non-identical auditory hair bundles are elastically coupled, their spontaneous oscillations can be quenched to form an amplitude death state. We show, in this state, the hair cells are quiet and ready to detect oscillatory stimulus with coupling-strength ...
arxiv
The genetics of hair cell development and regeneration.
Annual Review of Neuroscience, 2013 Sensory hair cells are exquisitely sensitive vertebrate mechanoreceptors that mediate the senses of hearing and balance. Understanding the factors that regulate the development of these cells is important, not only to increase our understanding of ear ...
A. Groves, Kaidi D. Zhang, D. Fekete
semanticscholar +1 more source
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.BX‐001N, a polyethylene glycol‐conjugated bilirubin 3α nanoparticle, is the first GMP‐grade, synthetic bilirubin‐based nanomedicine. It effectively attenuates acute renal injury, facilitates subacute renal recovery, and suppresses chronic fibrosis after renal ischemia/reperfusion injury via anti‐oxidant and immune‐modulating activity.
Ji‐Jing Yan +13 more
wiley +1 more source
Deletion of the Ca2+-activated potassium (BK) alpha-subunit but not the BK-beta-1-subunit leads to progressive hearing loss [PDF]
, 2005 The large conductance voltage- and Ca2+-activated potassium (BK) channel has been suggested to play an important role in the signal transduction process of cochlear inner hair cells.
Arntz, Claudia +18 more
core
Lateral Line Organ of Fish: A Possible Key to the Hair Cell Problem [PDF]
, 1962 Willem A. van Bergeijk, Gerard G. Harris
openalex +1 more source