Results 301 to 310 of about 554,359 (356)

Contributions of mirror-image hair cell orientation to mouse otolith organ and zebrafish neuromast function. [PDF]

Elife
Ono K, Jarysta A, Hughes NC, Jukic A, Chang HHV, Deans MR, Eatock RA, Cullen KE, Kindt KS, Tarchini B.   +9 more
europepmc   +1 more source

Long-range <i>Atoh1</i> enhancers maintain competency for hair cell regeneration in the inner ear. [PDF]

Proc Natl Acad Sci U S A
Shi T, Kim Y, Llamas J, Wang X, Fabian P, Lozito TP, Segil N, Gnedeva K, Crump JG.   +8 more
europepmc   +1 more source

Single-cell atlas comparison across vertebrates reveals auditory cell evolution and mechanisms for hair cell regeneration. [PDF]

Commun Biol
Wang Y, Wang H, Zhang P, Zhu B, Li W, Zhao X, Yan M, Song X, Lai F, Dong J, Cui J, Guo X, Wu HJ, Li J.   +13 more
europepmc   +1 more source

Gating of hair cell Ca²⁺channels governs the activity of cochlear neurons

Karagulyan N, Thirumalai A, Michanski S, Qi Y, Fang Q, Wang H, Ortner NJ, Striessnig J, Strenzke N, Wichmann C, Hua Y, Moser T.   +11 more
europepmc   +1 more source

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Hair cell development

Current Opinion in Neurobiology, 1993
Neurobiologists have been challenged by the desire to understand how the highly specialized ultrastructure of the sensory hair cells of the ear develops, how patterns of phenotypically distinct hair cells are formed and regenerate, and how their specific neural connections are formed.
J T, Corwin, M E, Warchol, M W, Kelley
openaire   +2 more sources

Hair follicle stem cells

Seminars in Cell & Developmental Biology, 2007
The increasing use of the hair follicle as a stem cell paradigm is due in part to the complex interplay between epithelial, dermal and other cell types, each with interesting differentiation potential and prospective therapeutic applications. This review focuses on research into the environmental niche, gene expression profiles and plasticity of hair ...
James M, Waters, Gavin D, Richardson, Colin A B, Jahoda   +2 more
openaire   +2 more sources

Hair Cell Regeneration

2019
Cochlear hair cells are mechanoreceptors of the auditory system and cannot spontaneously regenerate in adult mammals; thus hearing loss due to hair cell damage is permanent. In contrast, hair cells in nonmammalian vertebrates such as birds and in the zebrafish lateral line have the ability to regenerate after hair cell loss.
Yan, Chen, Shasha, Zhang, Renjie, Chai, Huawei, Li   +3 more
openaire   +2 more sources

Harvesting Human Hair Cells

Annals of Otology, Rhinology & Laryngology, 2000
The sensory hair cells of the inner ear are responsible for converting balance and hearing stimuli into electrical signals. Until recently, all previous studies of hair cell physiology had been performed on tissue obtained from non-mammals and rodents.
J S, Oghalai, J R, Holt, T, Nakagawa, T M, Jung, N J, Coker, H A, Jenkins, R A, Eatock, W E, Brownell   +7 more
openaire   +2 more sources

How hair cells hear: the molecular basis of hair-cell mechanotransduction

Current Opinion in Otolaryngology & Head & Neck Surgery, 2008
This review aims to summarize our current knowledge regarding mechanotransduction by hair cells and to highlight unresolved questions.Despite over a quarter of a century of electrophysiological data describing hair-cell mechanotransduction, the molecular basis of this process is just now being revealed.
Kelli R, Phillips, Anindita, Biswas, Janet L, Cyr   +2 more
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Models of Hair Cell Mechanotransduction

2007
Hair cell mechanotransduction is based on a finely tuned machinery residing in the hair bundle, the hair cell's receptive organelle. The machinery consists of a transduction channel, an adaptation motor, the tip link, and many other components that reside in the stereocilia.
Bechstedt, S., Howard, J.
openaire   +3 more sources