Results 141 to 150 of about 13,036 (186)
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Auditory amplification: outer hair cells pres the issue
Trends in Neurosciences, 2003Active feedback mechanisms in the ears of mammals amplify and tune the auditory response to sound stimuli, allowing these organisms to enjoy both exquisite sensitivity and sharp frequency selectivity. A requisite component of this feedback pathway has recently been identified.
Gwénaëlle S G, Géléoc +1 more
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Auditory collusion and a coupled couple of outer hair cells
Nature, 1999The discrepancies between measured frequency responses of the basilar membrane in the inner ear and the frequency tuning found in psychophysical experiments led to Bekesy's idea of lateral inhibition in the auditory nervous system. We now know that basilar membrane tuning can account for neural tuning, and that sharpening of the passive travelling wave
H B, Zhao, J, Santos-Sacchi
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Properties of auditory nerve responses in absence of outer hair cells
Journal of Neurophysiology, 19781. Recordings were made from chinchilla auditory nerve fibers after portions of the cochlear outer hair cell (OHC) population were destroyed with the antibiotic kanamycin. In most cases the inner hair cell (IHC) population was completely preserved as determined by phase-contrast microscopy.
P, Dallos, D, Harris
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Effect of absence of cochlear outer hair cells on behavioural auditory threshold
Nature, 1975THE function of the two populations of sensory cells in the mammalian inner ear is not well understood. Anatomical evidence indicates that the inner hair cells (IHCs) and the outer hair cells (OHCs) play separate roles in the transduction of acoustic stimuli1.
A, Ryan, P, Dallos
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Auditory Intensity Discrimination After Selective Loss of Cochlear Outer Hair Cells
Science, 1981The contributions of the inner and outer hair cells of the mammalian cochlea to auditory intensity discrimination were evaluated in a combined behavioral-anatomical study of the guinea pig. Intensity difference thresholds were unchanged from baseline values after selective destruction of outer hair cells, suggesting that those cells are unnecessary for
C A, Prosen +3 more
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Journal of Basic and Clinical Physiology and Pharmacology, 2010
The present study was designed to assess whether, in the presence of a depression of the cochlear amplifier i.e. a sensorineural hearing loss (SNHL), the inner hair cells (IHCs) require the presence of a normal endocochlear potential for transduction. An SNHL was induced by injecting salicylic acid (which binds to the motor protein prestin in the outer
Cahtia, Adelman +2 more
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The present study was designed to assess whether, in the presence of a depression of the cochlear amplifier i.e. a sensorineural hearing loss (SNHL), the inner hair cells (IHCs) require the presence of a normal endocochlear potential for transduction. An SNHL was induced by injecting salicylic acid (which binds to the motor protein prestin in the outer
Cahtia, Adelman +2 more
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The Journal of the Acoustical Society of America, 2023
Sensorineural hearing loss (SNHL) effects on neural coding and perception have been largely associated with outer-hair-cell (OHC) dysfunction (e.g., reduced cochlear gain, reduced compression, broadened tuning). However, both inner-hair-cell (IHC) and OHC dysfunction occur in common hearing-loss etiologies, e.g., noise-induced and age-related ...
Madhurima Patra +3 more
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Sensorineural hearing loss (SNHL) effects on neural coding and perception have been largely associated with outer-hair-cell (OHC) dysfunction (e.g., reduced cochlear gain, reduced compression, broadened tuning). However, both inner-hair-cell (IHC) and OHC dysfunction occur in common hearing-loss etiologies, e.g., noise-induced and age-related ...
Madhurima Patra +3 more
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Auditory brainstem response thresholds in a mouse mutant with selective outer hair cell loss
European Archives of Oto-Rhino-Laryngology, 1990Mutant animals with a particular type of cochlear pathology are an excellent model for studying the functional role of various cells of the cochlea. In homozygous WV/WV mutant mice we found a selective loss of outer hair cells as a constant defect with no progressive degeneration of the organ of Corti.
A, Schrott, K, Stephan, H, Spoendlin
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Factors influencing the length change of an auditory outer hair cell in a tight-fitting capillary
The Journal of the Acoustical Society of America, 1993A membrane theory with area and shear moduli is used to interpret an experimental configuration used by Zenner et al. [Acta Otolaryngol. 112, 248–253]. In that experiment an outer hair cell is drawn into a tight-fitting glass capillary and a negative pressure is applied to characterize the elasticity of the cell. Various assumptions concerning membrane
K H, Iwasa, R S, Chadwick
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Stretch sensitivity of the lateral wall of the auditory outer hair cell from the guinea pig
Neuroscience Letters, 1991The inner and outer hair cells of the mammalian hearing organ are mechano-transducer cells. Here we report evidence that the lateral wall of outer hair cells (OHCs) is a mechano-receptor. This mechano-sensitivity appears to complement that of the stereocilia.
K H, Iwasa, M X, Li, M, Jia, B, Kachar
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