Results 21 to 30 of about 46,629 (209)

LGR5 is a conserved marker of hair follicle stem cells in multiple species and is present early and throughout follicle morphogenesis

Scientific Reports, 2022
Hair follicle stem cells are key for driving growth and homeostasis of the hair follicle niche, have remarkable regenerative capacity throughout hair cycling, and display fate plasticity during cutaneous wound healing.
Kathryn M. Polkoff, Nithin K. Gupta, Adrian J. Green, Yanet Murphy, Jaewook Chung, Katherine L. Gleason, Sean G. Simpson, Derek M. Walker, Bruce Collins, Jorge A. Piedrahita   +9 more
doaj   +1 more source

Expression profile of long non-coding RNA in inner Mongolian cashmere goat with putative roles in hair follicles development

Frontiers in Veterinary Science, 2022
The hair follicle is a complex skin accessory organ, which determines hair growth. Long non-coding RNAs (lncRNAs) have been proven to play an important role in hair follicle development, but their specific mechanism is still unclear.
Rong Ma, Fangzheng Shang, Youjun Rong, Jianfeng Pan, Min Wang, Shuran Niu, Yunpeng Qi, Yanbo Li, Qi Lv, Zhiying Wang, Ruijun Wang, Rui Su, Zhihong Liu, Yanhong Zhao, Zhixin Wang, Jinquan Li, Jinquan Li, Jinquan Li, Yanjun Zhang   +18 more
doaj   +1 more source

The Hair Follicle as a Dynamic Miniorgan [PDF]

Current Biology, 2009
Hair is a primary characteristic of mammals, and exerts a wide range of functions including thermoregulation, physical protection, sensory activity, and social interactions. The hair shaft consists of terminally differentiated keratinocytes that are produced by the hair follicle.
Ralf Paus, Ralf Paus, Ruth Schmidt-Ullrich, Marlon R. Schneider   +3 more
openaire   +3 more sources

Advances in Understanding Hair Growth [version 1; referees: 2 approved]

F1000Research, 2016
In this short review, I introduce an integrated vision of human hair follicle behavior and describe opposing influences that control hair follicle homeostasis, from morphogenesis to hair cycling.
Bruno A. Bernard
doaj   +1 more source

Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation

Frontiers in Cell and Developmental Biology, 2020
There are many studies devoted to the role of hair follicle stem cells in wound healing as well as in follicle self-restoration. At the same time, the influence of the inflammatory cells on the hair follicle cycling in both injured and intact skin is ...
Elena I. Morgun, Ekaterina A. Vorotelyak
doaj   +1 more source

Autoantigen Discovery in the Hair Loss Disorder, Alopecia Areata: Implication of Post-Translational Modifications

Frontiers in Immunology, 2022
Alopecia areata (AA) is a chronic, multifactorial, polygenic, and heterogeneous disorder affecting growing hair follicles in susceptible individuals, which results in a non-scarring and reversible hair loss with a highly unpredictable course.
Shahnawaz D. Jadeja, Desmond J. Tobin, Desmond J. Tobin   +2 more
doaj   +1 more source

Serpins in the Human Hair Follicle [PDF]

Journal of Investigative Dermatology, 2000
Proteinases and their inhibitors are very likely to function as mediators or regulators of the hair growth cycle. Very little information is currently available, however, regarding the specific inhibitors present in human hair follicles at defined stages of their growth cycle.
Pamela J. Jensen, Da Wen Yu, Tien Yang, Robert M. Lavker, Tung-Tien Sun, Barbara Risse, Mark S. Baker   +6 more
openaire   +2 more sources

Pre-aggregation of scalp progenitor dermal and epidermal stem cells activates the WNT pathway and promotes hair follicle formation in in vitro and in vivo systems

Stem Cell Research & Therapy, 2019
Background Billions of dollars are invested annually by pharmaceutical companies in search of new options for treating hair loss conditions; nevertheless, the challenge remains.
Yiqun Su, Jie Wen, Junrong Zhu, Zhiwei Xie, Chang Liu, Chuan Ma, Qun Zhang, Xin Xu, Xunwei Wu   +8 more
doaj   +1 more source

Ginsenoside CK inhibits androgenetic alopecia by regulating Wnt/β‐catenin and p53 signaling pathways in AGA mice

Food Frontiers, 2023
Androgenetic alopecia (AGA) is one of the most common chronic skin diseases caused by the destruction of androgens in the body. It is caused by the excessive deposition of dihydrotestosterone around the hair follicle, resulting in hair follicle atrophy ...
Chao Fang, Haixia Yang, Chenhui Zhu, Daidi Fan, Jianjun Deng   +4 more
doaj   +1 more source

Hair Follicle Stem Cells [PDF]

Journal of Investigative Dermatology Symposium Proceedings, 2003
The workshop on Hair Follicle Stem Cells brought together investigators who have used a variety of approaches to try to understand the biology of follicular epithelial stem cells, and the role that these cells play in regulating the hair cycle.
Lavker, Robert M, Sun, Tung-Tien, Oshima, Hideo, Barrandon, Yann, Akiyama, Masashi, Ferraris, Corinne, Chevalier, Genevieve, Favier, Bertrand, Jahoda, Colin a B, Dhouailly, Danielle, Panteleyev, Andrei A, Christiano, Angela M   +11 more
openaire   +4 more sources