Results 21 to 30 of about 441,676 (302)

Hair follicle immune privilege and its collapse in alopecia areata

Experimental Dermatology, 2020
Anagen stage hair follicles (HFs) exhibit “immune privilege (IP)” from the level of the bulge downwards to the bulb. Both passive and active IP mechanisms protect HFs from physiologically undesired immune responses and limit immune surveillance.
M. Bertolini, K. McElwee, A. Gilhar, S. Bulfone-Paus, R. Paus   +4 more
semanticscholar   +1 more source

PI3K/Akt signaling pathway is essential for de novo hair follicle regeneration

Stem cell research & therapeutics, 2020
Cultured epidermal stem cells (Epi-SCs) and skin-derived precursors (SKPs) were capable of reconstituting functional hair follicles after implantation, while the signaling pathways that regulate neogenic hair follicle formation are poorly investigated ...
Yu Chen, Zhimeng Fan, Xiaoxiao Wang, Miaohua Mo, Shuxian Zeng, R. Xu, Xusheng Wang, Yaojiong Wu   +7 more
semanticscholar   +1 more source

Functional complexity of hair follicle stem cell niche and therapeutic targeting of niche dysfunction for hair regeneration

Journal of Biomedical Sciences, 2020
Stem cell activity is subject to non-cell-autonomous regulation from the local microenvironment, or niche. In adaption to varying physiological conditions and the ever-changing external environment, the stem cell niche has evolved with multifunctionality
Chih-Lung Chen, Wen-Yen Huang, E. Wang, K. Tai, Sung-Jan Lin   +4 more
semanticscholar   +1 more source

Hair follicle regional specificity in different parts of bay Mongolian horse by histology and transcriptional profiling

BMC Genomics, 2020
Background Different morphological structures of hairs having properties like defense and camouflage help animals survive in the wild environment.
Ruoyang Zhao, Wu Yihan, Yiping Zhao, Bei Li, Haige Han, Togtokh Mongke, Tugeqin Bao, Wenxing Wang, Manglai Dugarjaviin, Dongyi Bai   +9 more
doaj   +1 more source

Design of a biofluid-absorbing bioactive sandwich-structured Zn–Si bioceramic composite wound dressing for hair follicle regeneration and skin burn wound healing

Bioactive Materials, 2020
The deep burn skin injures usually severely damage the dermis with the loss of hair follicle loss, which are difficult to regenerate. Furthermore, severe burns often accompanied with large amount of wound exudates making the wound moist, easily infected,
Zhaowenbin Zhang, Wenbo Li, Ying Liu, Zhigang Yang, Lingling Ma, Zhuang Hui, Endian Wang, Chengtie Wu, Z. Huan, Feng Guo, Jiang Chang   +10 more
semanticscholar   +1 more source

Bioengineering the Hair Follicle [PDF]

Organogenesis, 2007
The hair follicle develops from the primitive embryonic epidermis as a result of complex epithelial-mesenchymal interactions. The full follicle, consisting of epithelial cylinders under control of a proximal lying mesenchymal papilla, grows in cycles giving rise to a new hair shaft during each cycle.
K, Stenn, S, Parimoo, Y, Zheng, T, Barrows, M, Boucher, K, Washenik   +5 more
openaire   +2 more sources

Hair Follicle Stem Cells [PDF]

Journal of Investigative Dermatology Symposium Proceedings, 2003
The workshop on Hair Follicle Stem Cells brought together investigators who have used a variety of approaches to try to understand the biology of follicular epithelial stem cells, and the role that these cells play in regulating the hair cycle.
Lavker, Robert M, Sun, Tung-Tien, Oshima, Hideo, Barrandon, Yann, Akiyama, Masashi, Ferraris, Corinne, Chevalier, Genevieve, Favier, Bertrand, Jahoda, Colin a B, Dhouailly, Danielle, Panteleyev, Andrei A, Christiano, Angela M   +11 more
openaire   +3 more sources

LGR5 is a conserved marker of hair follicle stem cells in multiple species and is present early and throughout follicle morphogenesis

Scientific Reports, 2022
Hair follicle stem cells are key for driving growth and homeostasis of the hair follicle niche, have remarkable regenerative capacity throughout hair cycling, and display fate plasticity during cutaneous wound healing.
Kathryn M. Polkoff, Nithin K. Gupta, Adrian J. Green, Yanet Murphy, Jaewook Chung, Katherine L. Gleason, Sean G. Simpson, Derek M. Walker, Bruce Collins, Jorge A. Piedrahita   +9 more
doaj   +1 more source

Immune modulation of hair follicle regeneration

npj Regenerative Medicine, 2020
The mammalian hair follicle undergoes repeated bouts of regeneration orchestrated by a variety of hair follicle stem cells. The last decade has witnessed the emergence of the immune niche as a key regulator of stem cell behavior and hair follicle ...
Waleed Rahmani, S. Sinha, J. Biernaskie
semanticscholar   +1 more source

Expression profile of long non-coding RNA in inner Mongolian cashmere goat with putative roles in hair follicles development

Frontiers in Veterinary Science, 2022
The hair follicle is a complex skin accessory organ, which determines hair growth. Long non-coding RNAs (lncRNAs) have been proven to play an important role in hair follicle development, but their specific mechanism is still unclear.
Rong Ma, Fangzheng Shang, Youjun Rong, Jianfeng Pan, Min Wang, Shuran Niu, Yunpeng Qi, Yanbo Li, Qi Lv, Zhiying Wang, Ruijun Wang, Rui Su, Zhihong Liu, Yanhong Zhao, Zhixin Wang, Jinquan Li, Jinquan Li, Jinquan Li, Yanjun Zhang   +18 more
doaj   +1 more source