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The Fate of Hair Follicle Melanocytes During the Hair Growth Cycle [PDF]
The fate of the follicular pigmentary unit during the hair growth cycle has long been one of the great enigmas of both hair follicle and pigment cell biology.
Botchkarev, Vladimir+3 more
core +1 more source
Background Different morphological structures of hairs having properties like defense and camouflage help animals survive in the wild environment.
Ruoyang Zhao+9 more
doaj +1 more source
The promotion of hair regeneration and growth heavily depends on the activation of Wnt/β‐catenin signalling in the hair follicle, including dermal papilla (DP).
Yeong Chan Ryu+9 more
semanticscholar +1 more source
Transient activaton of β-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours [PDF]
When β-catenin signalling is disturbed from mid-gestation onwards lineage commitment is profoundly altered in postnatal mouse epidermis. We have investigated whether adult epidermis has the capacity for β-catenin-induced lineage conversion without prior ...
Celso, Cristina Lo+2 more
core +1 more source
SIRT7 activates quiescent hair follicle stem cells to ensure hair growth in mice
Hair follicle stem cells (HFSCs) are maintained in a quiescent state until activated to grow, but the mechanisms that reactivate the quiescent HFSC reservoir are unclear.
Guo Li+12 more
semanticscholar +1 more source
SKPs Derive from Hair Follicle Precursors and Exhibit Properties of Adult Dermal Stem Cells [PDF]
SummaryDespite the remarkable regenerative capacity of mammalian skin, an adult dermal stem cell has not yet been identified. Here, we investigated whether skin-derived precursors (SKPs) might fulfill such a role. We show that SKPs derive from Sox2+ hair
Biernaskie, Jeffrey+6 more
core +2 more sources
Alopecia areata (AA) is a chronic, multifactorial, polygenic, and heterogeneous disorder affecting growing hair follicles in susceptible individuals, which results in a non-scarring and reversible hair loss with a highly unpredictable course.
Shahnawaz D. Jadeja+2 more
doaj +1 more source
A tube-like invagination of the epidermis from which the hair shaft develops and into which the sebaceous glands open; the follicle is lined by a cellular inner and outer root sheath of epidermal origin and is invested with a fibrous sheath derived from ...
semanticscholar +1 more source
Wnt/β-catenin signaling in dermal condensates is required for hair follicle formation [PDF]
Broad dermal Wnt signaling is required for patterned induction of hair follicle placodes and subsequent Wnt signaling in placode stem cells is essential for induction of dermal condensates, cell clusters of precursors for the hair follicle dermal papilla
Clavel, Carlos+7 more
core +1 more source
The hair follicle is a complex skin accessory organ, which determines hair growth. Long non-coding RNAs (lncRNAs) have been proven to play an important role in hair follicle development, but their specific mechanism is still unclear.
Rong Ma+18 more
doaj +1 more source