Results 51 to 60 of about 2,233 (118)

Mesenchymal stem cell-derived exosomes promote scalp rejuvenation through type XVII collagen regulation via the miR-21-5p/DKK2/Wnt pathway

Frontiers in Cell and Developmental Biology
BackgroundHair follicle aging is driven by COL17A1 proteolysis in hair follicle stem cells (HFSCs). Mesenchymal stem cell (MSC)-derived exosomes show promise in tissue regeneration, but their effects on COL17A1 and hair follicle aging remain unexplored ...
Shiyue Cui, Yuanyuan Huang, Duo Zeng, Jie Li, Chun Tang   +4 more
doaj   +1 more source

The GPR30 agonist G-1 promotes hair growth via Wnt/Hedgehog signaling in mice

Frontiers in Pharmacology
BackgroundGPR30 is a membrane-associated receptor involved in rapid, non-genomic estrogen signaling. Estrogen significantly influences hair growth and susceptibility to hair loss, with differences primarily driven by hormonal factors.
Mayu Yamano, Yuto Yamanaka, Shota Nishikawa, Yuki Masujima, Ryuji Ohue-Kitano, Ikuo Kimura, Ikuo Kimura, Ikuo Kimura   +7 more
doaj   +1 more source

Hair Growth Promoting Effect of Urticadioica L

Central Asian Journal of Medical Sciences, 2018
Objectives: We investigated the effect of Urticadioica L extracts on hair growth by using in-vitro and ex vivo study methods. Methods: Human single hair follicle and dermal papilla cells obtained from scalp skin samples of healthy volunteers.
Khaliun Myagmar, Enkhsaikhan Lkhagvasuren, Munkhbayar Semchin   +2 more
doaj   +1 more source

Revolutionary Approaches to Hair Regrowth: Follicle Neogenesis, Wnt/ß-Catenin Signaling, and Emerging Therapies

Cells
With alopecia affecting millions globally, recent advancements in the understanding of hair follicle biology have driven the development of novel therapies focused on hair regrowth. This review discusses two emerging therapeutic strategies: hair follicle
Apoorva Mehta, Mateen Motavaf, Danyal Raza, Alison J. McLure, Kofi D. Osei-Opare, Lindsey A. Bordone, Alejandro A. Gru   +6 more
doaj   +1 more source

Effects of UV Induced-Photoaging on the Hair Follicle Cycle of C57BL6/J Mice

Clinical, Cosmetic and Investigational Dermatology, 2021
Xu Zhai,1 Meihua Gong,1,2 Yixuan Peng,1 Daping Yang1 1Department of Plastic Surgery, The 2nd Hospital of Harbin Medical University, Harbin, People’s Republic of China; 2Department of Plastic and Cosmetic Surgery, Shenzhen People’s Hospital ...
Zhai X, Gong M, Peng Y, Yang D
doaj  

Platelet-rich plasma-derived exosomes stimulate hair follicle growth through activation of the Wnt/β-Catenin signaling pathway

Regenerative Therapy
Background: Androgenetic alopecia (AGA) is a common type of hair loss that affects a large segment of the global population, significantly influencing individuals' appearance and mental health.
Changpei Lu, Yunbu Ding, Rongshuang Zhang, Yimei Du, Lingbo Bi, Min Zhao, Chaofan Wang, Qiaofang Wu, Haixia Jing, Weixin Fan   +9 more
doaj   +1 more source

Inflammatory mediator TAK1 regulates hair follicle morphogenesis and anagen induction shown by using keratinocyte-specific TAK1-deficient mice.

PLoS ONE, 2010
Transforming growth factor-beta-activated kinase 1 (TAK1) is a member of the NF-kappaB pathway and regulates inflammatory responses. We previously showed that TAK1 also regulates keratinocyte growth, differentiation, and apoptosis. However, it is unknown
Koji Sayama, Kentaro Kajiya, Koji Sugawara, Shintaro Sato, Satoshi Hirakawa, Yuji Shirakata, Yasushi Hanakawa, Xiuju Dai, Yumiko Ishimatsu-Tsuji, Daniel Metzger, Pierre Chambon, Shizuo Akira, Ralf Paus, Jiro Kishimoto, Koji Hashimoto   +14 more
doaj   +1 more source

The development of hair follicles and nail

Developmental Biology
The hair follicle and nail unit develop and regenerate through epithelial-mesenchymal interactions. Here, we review some of the key signals and molecular interactions that regulate mammalian hair follicle and nail formation during embryonic development and how these interactions are reutilized to promote their regeneration during adult homeostasis and ...
Soung-Hoon Lee, Sarah Platt, Chae Ho Lim, Mayumi Ito, Peggy Myung   +4 more
openaire   +2 more sources

Structural and ultrastructural comparison of hair and feather follicles

یافته‌های نوین در علوم زیستی, 2014
Formations of feather and hair follicles during embryonic stage are nearly similar. The aim of the present research is to study the similarities and differences between these two follicles in adult pigeons and rats. To fulfill this task, feather and hair
Ahmad Gharzi
doaj  

Hair regeneration: Mechano-activation and related therapeutic approaches

Journal of Tissue Engineering
Hair regrowth through mechano-stimulation and other therapeutic approaches has emerged as a significant area of research in regenerative medicine. This review examines recent advances in hair regeneration strategies, with a particular focus on mechanical
Sun Young Nam, Shreyas Kumar Jain, Amal George Kurian, Ishik Jeong, Byung Cheol Park, Kiwon Ban, Jonathan C. Knowles, Hae-Won Kim   +7 more
doaj   +1 more source