Results 1 to 10 of about 6,940 (116)

Dermal Papilla Cell-Derived Extracellular Vesicles Increase Hair Inductive Gene Expression in Adipose Stem Cells via β-Catenin Activation

Cells, 2022
Recently, extracellular vesicle (EV)-mediated cell differentiation has gained attention in developmental biology due to genetic exchange between donor cells and recipient cells via transfer of mRNA and miRNA.
Taheruzzaman Kazi, Abir Nagata, Takatoshi Nakagawa, Takashi Matsuzaki, Shigeki Inui   +4 more
doaj   +3 more sources

Dermal papilla cells-conditioned medium attenuates oxidative stress-induced senescence via ferroptosis inhibition [PDF]

Scientific Reports
Skin photoaging results primarily from chronic ultraviolet (UV) exposure, which disrupts dermal homeostasis and promotes cellular senescence. Dermal papilla cell-conditioned medium (DPC-CM) has emerged as a promising cell-free approach for skin ...
Zha Ru, Yu Wu, Qian Qu, Yong Miao, Lei Zhu, Zhiqi Hu   +5 more
doaj   +2 more sources

Serotonin activates dermal papilla cells and promotes hair growth [PDF]

Scientific Reports
Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter that plays a vital role in regulating behavior, mood, memory, and gastrointestinal homeostasis. Although recent studies have identified an intestine-hair follicle link, potentially implicating 5-
Tatsuto Kageyama, Jieun Seo, Lei Yan, Sayuri Hamano, Junji Fukuda   +4 more
doaj   +2 more sources

Dermal Papilla Cells: From Basic Research to Translational Applications [PDF]

Biology
As an appendage of the skin, hair protects against ultraviolet radiation and mechanical damage and regulates body temperature. It also reflects an individual’s health status and serves as an important method of expressing personality.
He-Li Zhang, Xi-Xi Qiu, Xin-Hua Liao
doaj   +2 more sources

Sostdc1 Secreted from Cutaneous Lymphatic Vessels Acts as a Paracrine Factor for Hair Follicle Growth

Current Issues in Molecular Biology, 2022
In our previous study, we found that lymphatic vessels stimulate hair follicle growth through paracrine effects on dermal papilla cells. However, the paracrine factors secreted from cutaneous lymphatic vessels that can activate dermal papilla cells are ...
Sun-Young Yoon, Michael Detmar
doaj   +1 more source

Androgen receptor accelerates premature senescence of human dermal papilla cells in association with DNA damage. [PDF]

PLoS ONE, 2013
The dermal papilla, located in the hair follicle, expresses androgen receptor and plays an important role in hair growth. Androgen/Androgen receptor actions have been implicated in the pathogenesis of androgenetic alopecia, but the exact mechanism is not
Yi-Chien Yang, Hung-Chun Fu, Ching-Yuan Wu, Kuo-Ting Wei, Ko-En Huang, Hong-Yo Kang   +5 more
doaj   +1 more source

LncRNA H19 Overexpression Activates Wnt Signaling to Maintain the Hair Follicle Regeneration Potential of Dermal Papilla Cells

Frontiers in Genetics, 2020
Androgenetic alopecia (AGA) is a common hair loss disorder resulting in seriously abnormal social interaction and psychological disorders. Transplantation with autologous dermal papilla cells represents a prospective therapy.
Ningxia Zhu, En Lin, En Lin, Huan Zhang, Yang Liu, Guiyuan Cao, Congcong Fu, Le Chen, Yang Zeng, Bozhi Cai, Yanping Yuan, Bin Xia, Keng Huang, Changmin Lin   +13 more
doaj   +1 more source

Potential Natural Products Regulation of Molecular Signaling Pathway in Dermal Papilla Stem Cells

Molecules, 2023
Stem cells have demonstrated significant potential for tissue engineering and repair, anti-aging, and rejuvenation. Hair follicle stem cells can be found in the dermal papilla at the base of the follicle and the bulge region, and they have garnered ...
Zar Chi Soe, Zin Zin Ei, Kittichate Visuttijai, Pithi Chanvorachote   +3 more
doaj   +1 more source

Effects of Acanthus ebracteatus Vahl. extract and verbascoside on human dermal papilla and murine macrophage

Scientific Reports, 2022
Androgenic alopecia is a common type of hair loss, usually caused by testosterone metabolism generating dihydrotestosterone and hair follicular micro-inflammation. These processes induce dermal papilla cells to undergo apoptosis.
Vanuchawan Wisuitiprot, Kornkanok Ingkaninan, Panlop Chakkavittumrong, Wudtichai Wisuitiprot, Nitra Neungchamnong, Ruttanaporn Chantakul, Neti Waranuch   +6 more
doaj   +1 more source

Lrig1-expressing epidermal progenitors require SCD1 to maintain the dermal papilla niche

Scientific Reports, 2023
Niche cells are widely known to regulate stem/progenitor cells in many mammalian tissues. In the hair, dermal papilla niche cells are well accepted to regulate hair stem/progenitor cells.
Sophia Beng Hui Lim, Shang Wei, Andy Hee-Meng Tan, Maurice A. M. van Steensel, Xinhong Lim   +4 more
doaj   +1 more source