Results 1 to 10 of about 7,482 (117)

A Novel Approach to Pattern Dermal Papilla Spheroids in Dermal–Epidermal Composites Using Non-Adherent Microwell Arrays [PDF]

Bioengineering
Bioengineered dermal–epidermal composites (DECs) have demonstrated promise initiating skin regeneration and hair follicle neogenesis after injury. DECs in our work comprise a collagen matrix embedded with human dermal papilla cells (HDPCs) overlaid with ...
E. Cate Wisdom, Donald C. Aduba, Owen Lewis, Sandhya Xavier, Ernest O. N. Phillips, Kristin H. Gilchrist, Ira M. Herman, Vincent B. Ho, Thomas N. Darling, George J. Klarmann   +9 more
doaj   +2 more sources

Dermal papilla cells-conditioned medium attenuates oxidative stress-induced senescence via ferroptosis inhibition [PDF]

Scientific Reports
Skin photoaging results primarily from chronic ultraviolet (UV) exposure, which disrupts dermal homeostasis and promotes cellular senescence. Dermal papilla cell-conditioned medium (DPC-CM) has emerged as a promising cell-free approach for skin ...
Zha Ru, Yu Wu, Qian Qu, Yong Miao, Lei Zhu, Zhiqi Hu   +5 more
doaj   +2 more sources

CD133 defines hair-inductive cells in the dermal papilla [PDF]

Scientific Reports
A major contributing factor to the failure of cell-based human hair follicle (HF) engineering is our inability to cultivate highly specialized, inductive mesenchymal fibroblasts, which reside in a unique niche at the HF base, called the dermal papilla ...
Huangying Zhao, Linli Zhou, Lindsey G. Siegfried, Steven Boyce, Dorothy Supp, Thomas Andl, Yuhang Zhang   +6 more
doaj   +2 more sources

Androgen receptor accelerates premature senescence of human dermal papilla cells in association with DNA damage. [PDF]

PLoS ONE, 2013
The dermal papilla, located in the hair follicle, expresses androgen receptor and plays an important role in hair growth. Androgen/Androgen receptor actions have been implicated in the pathogenesis of androgenetic alopecia, but the exact mechanism is not
Yi-Chien Yang, Hung-Chun Fu, Ching-Yuan Wu, Kuo-Ting Wei, Ko-En Huang, Hong-Yo Kang   +5 more
doaj   +1 more source

Sostdc1 Secreted from Cutaneous Lymphatic Vessels Acts as a Paracrine Factor for Hair Follicle Growth

Current Issues in Molecular Biology, 2022
In our previous study, we found that lymphatic vessels stimulate hair follicle growth through paracrine effects on dermal papilla cells. However, the paracrine factors secreted from cutaneous lymphatic vessels that can activate dermal papilla cells are ...
Sun-Young Yoon, Michael Detmar
doaj   +1 more source

LncRNA H19 Overexpression Activates Wnt Signaling to Maintain the Hair Follicle Regeneration Potential of Dermal Papilla Cells

Frontiers in Genetics, 2020
Androgenetic alopecia (AGA) is a common hair loss disorder resulting in seriously abnormal social interaction and psychological disorders. Transplantation with autologous dermal papilla cells represents a prospective therapy.
Ningxia Zhu, En Lin, En Lin, Huan Zhang, Yang Liu, Guiyuan Cao, Congcong Fu, Le Chen, Yang Zeng, Bozhi Cai, Yanping Yuan, Bin Xia, Keng Huang, Changmin Lin   +13 more
doaj   +1 more source

Effects of Acanthus ebracteatus Vahl. extract and verbascoside on human dermal papilla and murine macrophage

Scientific Reports, 2022
Androgenic alopecia is a common type of hair loss, usually caused by testosterone metabolism generating dihydrotestosterone and hair follicular micro-inflammation. These processes induce dermal papilla cells to undergo apoptosis.
Vanuchawan Wisuitiprot, Kornkanok Ingkaninan, Panlop Chakkavittumrong, Wudtichai Wisuitiprot, Nitra Neungchamnong, Ruttanaporn Chantakul, Neti Waranuch   +6 more
doaj   +1 more source

HISTOLOGICAL STUDIES ON THE SKIN OF THE HEAD OF SUDANESE DUCK (CAIRINA MOSCHATA) DURING POST-HATCHING PERIOD [PDF]

Assiut Veterinary Medical Journal, 2020
The integumentary system of birds is quite different from that of mammals. The current study was applied on the skin covering the head of sudanese duck (cairina moschata) from hatching day until the skin became mature. In all different ages.
MADEHA HASHIM, AHMED HASSAN, DOAA MOKHTAR, HANAN ABD-ELHAFEEZ, NADA ABDELLAH   +4 more
doaj   +1 more source

Lrig1-expressing epidermal progenitors require SCD1 to maintain the dermal papilla niche

Scientific Reports, 2023
Niche cells are widely known to regulate stem/progenitor cells in many mammalian tissues. In the hair, dermal papilla niche cells are well accepted to regulate hair stem/progenitor cells.
Sophia Beng Hui Lim, Shang Wei, Andy Hee-Meng Tan, Maurice A. M. van Steensel, Xinhong Lim   +4 more
doaj   +1 more source

Potential Natural Products Regulation of Molecular Signaling Pathway in Dermal Papilla Stem Cells

Molecules, 2023
Stem cells have demonstrated significant potential for tissue engineering and repair, anti-aging, and rejuvenation. Hair follicle stem cells can be found in the dermal papilla at the base of the follicle and the bulge region, and they have garnered ...
Zar Chi Soe, Zin Zin Ei, Kittichate Visuttijai, Pithi Chanvorachote   +3 more
doaj   +1 more source