Cells, 2022 iPSCs and their derivatives are the most promising cell sources for creating skin equivalents. However, their properties are not fully understood. In addition, new approaches and parameters are needed for studying cells in 3D models without destroying ...
Alena Kashirina +8 more
doaj +1 more source
5α-Reductase Activity in Cultured Human Dermal Papilla Cells from Beard Compared with Reticular Dermal Fibroblasts [PDF]
, 1990 The activity of 5α -reductase was assessed in cultured human beard dermal papilla cells and reticular dermal fibroblasts to elucidate the mechanism of androgen action in promoting the growth of beards in men. The monolayer was incubated with 50nM of [1,2-
Itami, Satoshi +2 more
core +1 more source
Canine adipose-derived stem cell aggregates as a viable substitute to actual canine dermal papillae [PDF]
Macedonian Veterinary Review, 2015 Hair loss is a major dermatological disease in veterinary and human medicine. Active studies on hair regeneration with mesenchymal stem cells have been performed in an effort to solve the limitations of conservative treatments in human medicine.
Sohee Bae +8 more
doaj +1 more source
Hair follicle germs containing vascular endothelial cells for hair regenerative medicine
Scientific Reports, 2021 Hair regenerative medicine has emerged as a promising approach for the treatment of severe hair loss. Recent advances in three-dimensional tissue engineering, such as formation of hair follicle germs (HFGs), have considerably improved hair regeneration ...
Tatsuto Kageyama +2 more
doaj +1 more source
Platelet factor 4 inhibits human hair follicle growth and promotes androgen receptor expression in human dermal papilla cells [PDF]
PeerJ, 2020 Platelet-rich plasma (PRP) has been reported recently as a potential therapeutic approach for alopecia, such as androgenetic alopecia, but the exact mechanisms and effects of specific components of this recipe remain largely unknown.
Ke Sha +9 more
doaj +2 more sources
Differences in Expression of Specific Biomarkers Distinguish Human Beard from Scalp Dermal Papilla Cells [PDF]
, 2006 Androgen exposure stimulates the growth of beard hair follicles. The follicle dermal papilla appears to be the site of androgen action; however, the molecular mechanisms that regulate this process are not well understood.
Kolpak, Meredith L. +11 more
core +1 more source
Journal of Biomedicine and Translational Research, 2017 Background: Oligonol® (OLG) is a functional food product and ingredient for cosmetics derived from a lychee fruit polyphenol. It has been reported to act on the skin as an anti-inflammatory and prevent UVB-induced skin damage.
Koji Wakame +6 more
doaj +1 more source
Randomized preclinical study of machine perfusion in vascularized composite allografts
BJS (British Journal of Surgery), EarlyView., 2020 This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin +7 more
wiley +1 more source
GMP-Compliant Culture of Human Hair Follicle Cells for Encapsulation and Transplantation
Cell Transplantation, 2012 Human hair follicle cells, both bulge and dermal papilla cells, were isolated and cultured in a GMP cell factory, in order to obtain an in vitro hair follicle source for encapsulation end transplantation in alopecia regenerative cell therapy. An in vitro
Mario Marazzi +12 more
doaj +1 more source
The homing of exogenous hair follicle mesenchymal stem cells into hair follicle niches
JCI Insight, 2023 Hair loss is a debilitating condition associated with the depletion of dermal papilla cells (DPCs), which can be replenished by dermal sheath cells (DSCs).
Kaitao Li +13 more
doaj +1 more source