Results 51 to 60 of about 47,731 (166)

A Single Subcutaneous Dose of BMD-1141 Stimulates Hair Regrowth Comparable to Daily, High-Dose Ruxolitinib in a Mouse Model of Alopecia Areata

Cells
Alopecia areata (AA) is an autoimmune disorder of hair loss resulting from a T-cell mediated attack on hair follicles. Three Janus kinase (JAK) inhibitors have been approved for the treatment of moderate-to-severe alopecia areata; however, safety ...
Robert Gensure, Brett King, Stephen Sikkink, Andrei Mardaryev, Robyn Goforth   +4 more
doaj   +1 more source

Estrogen leads to reversible hair cycle retardation through inducing premature catagen and maintaining telogen.

PLoS ONE, 2012
Estrogen dysregulation causes hair disorder. Clinical observations have demonstrated that estrogen raises the telogen/anagen ratio and inhibits hair shaft elongation of female scalp hair follicles.
Hui-min Hu, Shou-bing Zhang, Xiao-hua Lei, Zhi-li Deng, Wei-xiang Guo, Zhi-fang Qiu, Shuang Liu, Xin-yue Wang, He Zhang, En-kui Duan   +9 more
doaj   +1 more source

In Vitro Culturing and Harvesting of Human Plucked Hair Follicles

Journal of Bioresource Management, 2015
Human hair follicles are miniature hair growing organs. A common human hair disorder is androgenetic alopecia (AGA), which becomes a medical problem only when the hair loss is subjectively seen as excessive, premature, and distressing on the scalp.
Iram Rehman, Attika Rehman, Samina Jalil
doaj   +1 more source

TLR2 regulates hair follicle cycle and regeneration via BMP signaling

eLife
The etiology of hair loss remains enigmatic, and current remedies remain inadequate. Transcriptome analysis of aging hair follicles uncovered changes in immune pathways, including Toll-like receptors (TLRs).
Luyang Xiong, Irina Zhevlakova, Xiaoxia Z West, Detao Gao, Rakhilya Murtazina, Anthony Horak, J Mark Brown, Iuliia Molokotina, Eugene A Podrez, Tatiana V Byzova   +9 more
doaj   +1 more source

Diode laser epilation of urethral hair follicles following urethroplasty

Urology Research and Practice, 2019
The patient, a 35-year-old male, presented at our clinic complaining of occasional difficulty in urination and the blurry urination. The patient’s history included eleven cases of internal urethrotomy, urethral catheter insertion, urethral dilatation ...
Coşkun Şahin, Mehmet Kalkan
doaj   +1 more source

Dermal T cell immunity and key regulatory signaling pathways: Implications in immune-mediated alopecia and hair regeneration

Genes and Diseases
Mammalian hair follicles undergo periodic regeneration, with recent research highlighting the immunological niche as a critical regulator of stem cell activity and hair follicle regeneration.
Nana Tao, Qingru Sun, Yuyuan Ying, Yitao Wang, Jianli Gao   +4 more
doaj   +1 more source

Immunohistochemical assessment of SOX10 and its relation to the immune cellular infiltrate in alopecia areata follicles

Journal of the Egyptian Women’s Dermatologic Society
Background Alopecia areata (AA) is a nonscarring patchy hair loss that can extend to affect all body hair. Many hypotheses for autoimmunity onset in AA have been reported and the immune privilege collapse theory is the most accepted.
Sherif S. Awad, Amal AbdelRahman, Manal Gabril, Keroles Nageh, Ahmed F. Rezk   +4 more
doaj   +1 more source

EFECTIVITY MINOXIDIL AS A TREATMENT OF ALOPECIA AREATA

e-Jurnal Medika Udayana, 2014
Alopecia areata is hair loss with patchy formation, the most common cause of alopecia nonscarring. Occurred in 1,7 % of Americans aged 50 years. Canoccurs in both sexes, all races and any age.
Wayan Evie Frida Yustin
doaj  

Combining multiomics to analyze the molecular mechanism of hair follicle cycle change in cashmere goats from Inner Mongolia

Frontiers in Veterinary Science
Sheep body size can directly reflect the growth rates and fattening rates of sheep and is also an important index for measuring the growth performance of meat sheep.Inner Mongolia Cashmere Goat is a local excellent breed of cashmere and meat dual-purpose,
Chongyan Zhang, Chongyan Zhang, Qing Qin, Qing Qin, Zhichen Liu, Zhichen Liu, Yichuan Wang, Yichuan Wang, Mingxi Lan, Mingxi Lan, Dan Zhao, Dan Zhao, Jingwen Zhang, Jingwen Zhang, Zhixin Wang, Zhixin Wang, Jinquan Li, Jinquan Li, Jinquan Li, Zhihong Liu, Zhihong Liu, Zhihong Liu, Zhihong Liu   +22 more
doaj   +1 more source

Enhancing hair regeneration: Recent progress in tailoring nano-structured lipid carriers through surface modification strategies

ADMET and DMPK
Background and purpose: Hair loss is a prevalent problem affecting millions of people worldwide, necessitating innovative and efficient regrowth approaches.
Omar M. Atrooz, Nasim Reihani, M. R. Mozafari, Ahmad A. Salawi, Elham Taghavi   +4 more
doaj   +1 more source