Results 61 to 70 of about 751,056 (354)

Growth in Cartilage-Hair Hypoplasia [PDF]

open access: yesPediatric Research, 1992
Cartilage-hair hypoplasia is an osteochondrodysplasia with short-limbed short stature. The cartilage-hair hypoplasia gene is exceptionally prevalent in Finland; more than 100 patients have been identified. We have analyzed the growth of 100 Finnish patients and present cartilage-hair hypoplasia-specific growth charts of height and weight for height ...
O, Mäkitie, J, Perheentupa, I, Kaitila
openaire   +2 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Fisetin Promotes Hair Growth by Augmenting TERT Expression

open access: yesFrontiers in Cell and Developmental Biology, 2020
Although thinning hair and alopecia are not recognized as severe diseases, hair loss has implications for mental health and quality of life; therefore, a large number of studies have been carried out to develop novel hair growth agents.
Chisato Kubo   +4 more
doaj   +1 more source

Revisiting Cosmic No-Hair Theorem for Inflationary Settings

open access: yes, 2012
In this work we revisit Wald's cosmic no-hair theorem in the context of accelerating Bianchi cosmologies for a generic cosmic fluid with non-vanishing anisotropic stress tensor and when the fluid energy momentum tensor is of the form of a cosmological ...
A. Maleknejad   +5 more
core   +1 more source

Root hairs matter at field scale for maize shoot growth and nutrient uptake, but root trait plasticity is primarily triggered by texture and drought [PDF]

open access: hybrid, 2022
Doris Vetterlein   +16 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Effectiveness of a Novel Compound HAIR & SCALP COMPLEX on Hair Follicle Regeneration

open access: yesCosmetics
Background: People lose between 50 and 100 hairs a day and generate new ones from stem cells in hair follicles, but in those suffering from baldness, the stem cells remain inactive and are unable to regenerate new hair.
Greta Ferruggia   +3 more
doaj   +1 more source

Alopecia areata: a multifactorial autoimmune condition [PDF]

open access: yes, 2019
Alopecia areata is an autoimmune disease that results in non-scarring hair loss, and it is clinically characterised by small patches of baldness on the scalp and/or around the body. It can later progress to total loss of scalp hair (Alopecia totalis) and/
Butcher, John P.   +3 more
core   +1 more source

Heparanase Regulates Murine Hair Growth [PDF]

open access: yesThe American Journal of Pathology, 2005
Heparanase is an endoglycosidase that cleaves heparan sulfate, the main polysaccharide component of the extracellular matrix. Heparan sulfate moieties are responsible for the extracellular matrix barrier function, as well as for sequestration of heparin-binding growth factors in the extracellular matrix.
Eyal, Zcharia   +7 more
openaire   +2 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

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