Drug-induced stress granule formation protects sensory hair cells in mouse cochlear explants during ototoxicity [PDF]
, 2019 Stress granules regulate RNA translation during cellular stress, a mechanism that is generally presumed to be protective, since stress granule dysregulation caused by mutation or ageing is associated with neurodegenerative disease.
Dawson, Sally J. +6 more
core +2 more sources
Hair loss in males versus females: An Ayurveda review
Journal of Ayurveda, 2023 Objectives: Modern scientific research has distinguished between the male and female hair loss while Ayurveda does not explicitly make that demarcation. The present work describes the male and female hair loss distinctions from Ayurveda perspective. Data
Sanjay Tamoli +7 more
doaj +1 more source
Defective Tmprss3-Associated Hair Cell Degeneration in Inner Ear Organoids [PDF]
, 2019 Mutations in the gene encoding the type II transmembrane protease 3 (TMPRSS3) cause human hearing loss, although the underlying mechanisms that result in TMPRSS3-related hearing loss are still unclear.
Alex, Alpha L. +8 more
core +1 more source
Deletion of the Ca2+-activated potassium (BK) alpha-subunit but not the BK-beta-1-subunit leads to progressive hearing loss [PDF]
, 2005 The large conductance voltage- and Ca2+-activated potassium (BK) channel has been suggested to play an important role in the signal transduction process of cochlear inner hair cells.
Arntz, Claudia +18 more
core +2 more sources
Hair loss impact on quality of life of patients with oncological diseases – pilot study [PDF]
Farmacja Polska, 2023 In oncological treatment hair loss is one of the adverse events related to the use of cytostatic drugs. Hair loss is a problem that to affects people’s well-being and quality of life.
Monika Szkultecka-Dębek +3 more
doaj +1 more source
Journal of Family Medicine and Primary Care, 2021 Background: Alopecia is a common health condition that can be associated with social and psychological consequences. Aims: This study aims to estimate the prevalence of hair loss and its associated risk factors among primary healthcare center (PHC ...
Abeer R Alomaish +8 more
doaj +1 more source
Quality of life and maladjustment associated with hair loss in women with alopecia androgenetica [PDF]
, 1994 Quality of life and maladjustment related to hair loss were studied by means of a standardized interview in a group of 58 women with alopecia androgenetica who applied for treatment at the Department of Dermatology.
Donk, J. (J.) van der +4 more
core +1 more source
The relationship between local scalp skin temperature and cutaneous perfusion during scalp cooling [PDF]
, 2007 Cooling the scalp during administration of chemotherapy can prevent hair loss. It reduces both skin blood flow and hair follicle temperature, thus affecting drug supply and drug effect in the hair follicle. The extent to which these mechanisms contribute
Janssen, Francis-Paul E.M. +4 more
core +4 more sources
Controlling Hair Loss by Regulating Apoptosis in Hair Follicles: A Comprehensive Overview
Biomolecules, 2023 Apoptosis is a physiological process that occurs in all cell types of the human body, and it profoundly changes the fate of hair by affecting hair follicle cells.
Wuji Wang +4 more
doaj +1 more source
Dermatology and Therapy, 2023 Introduction Ritlecitinib demonstrated efficacy in patients with alopecia areata (AA) in the ALLEGRO phase 2b/3 study (NCT03732807). However, hair loss presentation may vary based on location (e.g., scalp, eyebrow/eyelash, body).
Diamant Thaçi +10 more
doaj +1 more source