Results 61 to 70 of about 836,616 (347)

Progressive auditory neuropathy in patients with Leber's hereditary optic neuropathy [PDF]

open access: yes, 2004
Objective: To investigate auditory neural involvement in patients with Leber's hereditary optic neuropathy (LHON).Methods: Auditory assessment was undertaken in two patients with LHON.
Ceranic, B, Luxon, LM
core   +2 more sources

Citalopram and Hair Loss [PDF]

open access: yesThe Primary Care Companion For CNS Disorders, 2000
Sir: Selective serotonin reuptake inhibitors (SSRIs) are the mainstay of treatment for a wide variety of psychiatric disorders including mood and anxiety disorders. Hair loss with the SSRIs, tricyclic antidepressants (TCAs), and other classes of antidepressants has been anecdotally reported.1–6 We report a case of a 50-year-old white woman with bipolar
Sanjay, Gupta, Prakash S., Masand
openaire   +2 more sources

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

open access: yesFEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar   +3 more
wiley   +1 more source

Absence of plastin 1 causes abnormal maintenance of hair cell stereocilia and a moderate form of hearing loss in mice [PDF]

open access: yes, 2014
Hearing relies on the mechanosensory inner and outer hair cells (OHCs) of the organ of Corti, which convert mechanical deflections of their actin-rich stereociliary bundles into electrochemical signals. Several actin-associated proteins are essential for
Bullen, A.   +7 more
core   +3 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Considerations and recommendations on camouflage in alopecia in Black women

open access: yesInternational Journal of Women's Dermatology, 2023
Alopecia is among the leading dermatological concerns affecting Black women. For many women, hair is a central component of identity and self-expression, the loss of which can have significant psychosocial effects.
Marta Taye, BA   +3 more
doaj   +1 more source

The nicotinic receptor of cochlear hair cells: A possible pharmacotherapeutic target? [PDF]

open access: yes, 2009
Mechanosensory hair cells of the organ of Corti transmit information regarding sound to the central nervous system by way of peripheral afferent neurons.
Elgoyhen, Ana Belen   +2 more
core   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

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