Results 191 to 200 of about 400,479 (276)

Dietary Collagen Supplementation as a Strategy for Skin Health: A Narrative Review of Clinical Effects on Skin, Hair, Nails, and Wound Healing. [PDF]

Nutrients
Biełach-Bazyluk A, Jurga M, Flisiak I, Zbroch E.   +3 more
europepmc   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

Advanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie, Yanbo Zhu, Wenhua Jiang, Haobo Xie, Yaojia Li, Mengjie Hu, Kezheng Li, Huan Yu, Yixuan Pan, Chaoyi Jiang, Xueqin Song, Dongsheng Fan, Binbin Deng   +12 more
wiley   +1 more source

Comparative Cochlear-Vestibular Aging Reveals Age-Aligned Mitochondrial Ultrastructural Burden, Mitophagy-Autophagy Remodeling, Synaptic Uncoupling, and Sensory Functional Decline. [PDF]

Aging Cell
Xie J, Zhang X, Tian J, Yan Y, Shi K, Pan Y, Zhang Y, Chen Z, Sun J, Lv H, Chen J, Ren X, Kamogashira T, Zhang X, Gao Y.   +14 more
europepmc   +1 more source

Dual Lineages of Langerhans Cells Cooperate to Restore the Immune Barrier after Skin Injury

Advanced Science, EarlyView.
After skin injury, the epidermal immune barrier is rebuilt by two sources of Langerhans cells. Resident Langerhans cells first move into the wound during re‐epithelialization, guided by CXCR2 signaling. Later, recruited monocytes become long‐lived Langerhans cells.
Axel D. Schmitter‐Sánchez, Nicholas Basista, Sudhanshu Mishra, Hyeri Kim, Audrey Bench, Catherine Matte‐Martone, Min‐Soo Seo, Gun Woo Lee, Sangbum Park   +8 more
wiley   +1 more source

Ethnobotanical survey of medicinal plants traditionally used in Daulat Nagar, Punjab, Pakistan. [PDF]

J Ethnobiol Ethnomed
Hussain K, Sadia H, Alshaqhaa MA, Nawaz K, Shahbaz A, Arshad N, Ijaz S, Imran T, Ahsan T.   +8 more
europepmc   +1 more source

Heat Stress Promotes Fibroblast‐Derived WNT5A Secretion Through m6A Modification to Activate Melanogenesis

Advanced Science, EarlyView.
Heat stress promotes WNT5A secretion from fibroblasts via METTL3/YTHDC1‐dependent m6A methylation. Subsequently, WNT5A binds to FZD10 on melanocytes, activating β‐catenin‐driven melanogenesis. ABSTRACT As the impact of global warming continues to intensify, the effects of heat stress on the skin are becoming increasingly evident.
Yuanyuan Wan, Yaqing Wen, Yushan Zhang, Lan Zhang, Jianjian Zhu, Zhen Tang, Ling Jiang, Chuhan Fu, Shu Zhou, Keyi Zhang, Jiangfeng Huang, Li Lei, Jing Chen, Qinghai Zeng   +13 more
wiley   +1 more source

A GMP-compliant formulation of regeneratively active polyphosphate for wound healing and skin regeneration.

Biomater Sci
Müller WEG, Neufurth M, La X, Nassabi H, Brösicke M, Dobmeyer R, Muñoz-Espí R, Wu C, Ushijima H, Schröder HC, Wang X.   +10 more
europepmc   +1 more source

Adsorption of Cationic Lignin Derivatives on Negatively Charged Model Surfaces and Hair Fibers: Implications for Hair Conditioning Performance. [PDF]

ACS Appl Mater Interfaces
Fernandes C, Cabaça D, Guzmán E, Serra R, Eivazi A, Norgren M, Alves L, Medronho B, Rasteiro MDG, Varela C.   +9 more
europepmc   +1 more source

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

Advanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li, Haojie Fu, Zhe Wang, Xuanzhou Chen, Ruhong Zhang, Xudong Wang, Louis D. Zhang, Xiang Li, Datao Li   +8 more
wiley   +1 more source

Research Progress on Platelet-Rich Plasma (PRP) in the Treatment of Androgenetic Alopecia. [PDF]

J Cosmet Dermatol
Zhong Z, Luo L, Zhao L, Yue X, Lu Y.
europepmc   +1 more source