Results 111 to 120 of about 903,495 (253)

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

open access: yesAdvanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang   +11 more
wiley   +1 more source

Visual analysis of research progress and trend on hairy roots

open access: yesFrontiers in Plant Science
Hairy root is a special form of root tissue, which is induced by Rhizobium rhizogenes and could mediate genetic transformation after the infection of explants.
Yu-Ping Zheng
doaj   +1 more source

Production of gericudranins by hairy root culture of Cudrania tricuspidata

open access: yes, 1995
Production of new flavanol derivatives with cytotoxic activity, gericudranin A and B, was studied by using hairy root cultures of Cudrania tricuspidata. Schenk and Hildebrandt (SH) medium was chosen for root growth and gericudranin production.
Ick Dong Yoo   +3 more
core  

Optimizing carrot hairy root production for monoxenic culture of arbuscular mycorrhizal fungi in Iran

open access: yes, 2006
This research describes the optimized method of carrot hairy roots production for monoxenic culture of Arbuscular Mycorrhizal Fungi (AMF) in Iran. Inoculation of mature carrot root sections was carried out using four isolates of Agrobacterium rhizogenes ...
Goltapeh, E. Mohammadi   +3 more
core   +1 more source

Immediate Growth Control in Response to Boiling Histotripsy is Prognostic for Intratumoral Immune Activation

open access: yesAdvanced Science, EarlyView.
Boiling Histrotripsy (BH), a mechanical form of focused ultrasound (FUS), allows for non‐invasive and non‐ionizing tissue destruction. Utilizing a BH treatment protocol that yielded bifurcating primary tumor growth responses, we found that immediate BH‐induced tumor growth control identifies tumors with acute reductions in antigen‐presenting cells (APC)
Lydia E. Kitelinger   +8 more
wiley   +1 more source

THE EFFECT OF SUBCULTURE ON HAIRY ROOT DEVELOPMENT OF JAVA GINSENG (Talinum paniculatumGaertn.) [PDF]

open access: yes, 2011
Java ginseng (Talinum paniculatum Gaertn.)root was reported to have efficacy similar to the Korean ginseng(Panax ginseng)root. Hairy root induction of Java ginseng on free hormone solid medium Murashige and Skoog (MS) using genetic ...
Manuhara, Yosephine Sri Wulan   +1 more
core   +1 more source

Elicitation Effects of Fungal Extracts on Silymarin Accumulation in Silybum marianum (L.) Gaertn Hairy Root Culture

open access: yesJournal of Medicinal Plants, 2013
Background: Silymarin, extracted from the seeds of milk thistle (Silybum marianum (L.) Gaertn) is mostly used for liver disease treatment. Hairy root cultures derived from S. marianum are able to produce silymarin.
T Hasanloo   +3 more
doaj  

Hairy root induction and plant regeneration in Hypericum perforatum L

open access: yes, 2003
Hypericum perforatum L. (Family: Clusiaceae) is a medicinal plant well known for its antidepressant and antiviral properties. The blooming aerial part of the plant contains active pharmaceutical metabolites (hypericins, hyperforins, xanthones, flavonoids,
DI GUARDO A.   +6 more
core  

Modulating Calcium Homeostasis via a Biomimetic Scaffold to Rescue Diabetic Ischemic Wounds

open access: yesAdvanced Science, EarlyView.
This strategy addresses impaired microcirculation and loss of extracellular matrix (ECM) guidance in diabetic wound healing. Musc@CP, a nanofibrous dressing combining an ECM‐mimetic chitosan‐pullulan scaffold with muscone, enhances perfusion by attenuating intracellular Ca2+ overload‐associated endothelial dysfunction.
Xiang Zheng   +14 more
wiley   +1 more source

Dual Lineages of Langerhans Cells Cooperate to Restore the Immune Barrier after Skin Injury

open access: yesAdvanced Science, EarlyView.
After skin injury, the epidermal immune barrier is rebuilt by two sources of Langerhans cells. Resident Langerhans cells first move into the wound during re‐epithelialization, guided by CXCR2 signaling. Later, recruited monocytes become long‐lived Langerhans cells.
Axel D. Schmitter‐Sánchez   +8 more
wiley   +1 more source

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