Results 71 to 80 of about 554,844 (332)

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla   +16 more
wiley   +1 more source

Improvement of Artemisinin Production in Hairy Roots Culture of Artemisia annua L. by Staphylococcus aureus

open access: yesJournal of Medicinal Plants, 2013
Background: Artemisinin is an important plant secondary metabolite with anti-malaria, anti-viral and anti-cancer properties. In recent years many efforts have been made to improve artemisinin production through plant tissue culture (such as hairy roots).
E Bandeh-Ali, M Keyhanfar, G Asghari
doaj  

Agrobacterium rhizogenes-mediated hairy roots transformation as a tool for exploring aluminum-responsive genes function

open access: yesFuture Science OA, 2019
Aim: To develop a useful alternative approach to evaluate the gene function in hairy roots. Methods: Arabidopsis and tobacco (wild-type or mutant) were a host for Agrobacterium rhizogenes transformation.
A. Daspute   +6 more
semanticscholar   +1 more source

Poly(hydroxy‐oxazolidone) Thermoplastic Elastomers for Safer, Greener and Customizable Blood‐Contacting Medical Devices

open access: yesAdvanced Healthcare Materials, EarlyView.
A poly(hydroxy‐oxazolidone) (PHOx) is synthesized from CO2‐based precursors, enabling the up‐cycling of this waste material. After synthesis, PHOx shows thermoplastic properties, and can therefore be processed by many temperature‐dependent techniques. PHOx is hemocompatible, anti‐adhesive, and biocompatible, which is demonstrated in vitro and in vivo ...
Sofia F. Melo   +11 more
wiley   +1 more source

Advancing from MOFs and COFs to Functional Macroscopic Porous Constructs

open access: yesAdvanced Materials, EarlyView.
This review study investigates the recent progress and methodologies for manufacturing metal–organic framework (MOF) or covalent–organic framework (COF)‐based 3D structured macroscopic porous constructs with high structural integrity, providing the possibility to control their porosity across dimensions.
Seyyed Alireza Hashemi   +8 more
wiley   +1 more source

Enhancement of Tropane Alkaloid Production among Several Clones and Explants Types of Hairy Root of Atropa belladonna L. [PDF]

open access: yesJournal of Medicinal Plants and By-products, 2012
Agrobacterium rhizogenes (pRi), a causative agent of hairy root disease, effectively induces hairy root formation in a variety of plant species. In our study four bacterial strains AR15834, A4, 9435 and C318 and three explants types leaf, stems and roots,
doaj  

Small-Scale Bioreactor for Sterile Hydroponics and Hairy Roots: Metabolic Diversity and Salicylic Acid Exudation by Hairy Roots of Hyoscyamus niger

open access: yesApplied Sciences, 2019
The volume and complexity of commercial bioreactors for sterile hydroponics and hairy roots are too large for comparative analysis of many cultures. Here a small-scale bioreactor fabricated from standard glass materials and suitable for both airlift and ...
Zana Jamal Kareem   +6 more
doaj   +1 more source

A review on the application of hairy roots in removing phenolic compounds from aqueous solutions [PDF]

open access: yesسلامت و محیط, 2023
Background and Objective: The presence of toxic compounds, including phenol, due to industrial development, poses a threat to the environment. Utilizing hairy roots has emerged as a potential method to remove these toxins. This review aims to explore the
Tahereh Ebrahimi   +3 more
doaj  

Kinetic growth model for hairy root cultures

open access: yesMathematical Biosciences and Engineering, 2019
The growth of hairy root cultures in bioreactors yields a complex root network and limits nutrient availability to the inner core of the root bed. A kinetic growth model to explain the growth in terms of length of individual primary and their higher order branches has been developed.
Sambasiva Rao Katuri   +2 more
openaire   +3 more sources

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

open access: yesAdvanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang   +3 more
wiley   +1 more source

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