Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
The unified transform method for linear initial-boundary value problems: a spectral interpretation [PDF]
It is known that the unified transform method may be used to solve any well-posed initial-boundary value problem for a linear constant-coefficient evolution equation on the finite interval or the half-line.
Smith, David A.
core
Hartman-type comparison theorems for half-linear differential equations of the second order
Comparison theorem of the Hartman type for a continuous family of nonlinear differential equations of the form $$ \big(p(t, \lambda)\varphi(u')\big)' + q(t,\lambda) \varphi(u) = 0, \lambda \geq 0, \quad \tag{ $\rm E_\lambda$}$$ where $ p \in \mathrm{C ...
Jaroslav Jaroš
doaj +1 more source
Dynamics and Lax-Phillips scattering for generalized Lamb models
This paper treats the dynamics and scattering of a model of coupled oscillating systems, a finite dimensional one and a wave field on the half line. The coupling is realized producing the family of selfadjoint extensions of the suitably restricted self ...
Albeverio S +13 more
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
A remark on the linearization technique in half-linear oscillation theory [PDF]
We show that oscillatory properties of the half-linear second order differential equation \[(r(t)\Phi(x'))'+c(t)\Phi(x)=0,\qquad\Phi(x)=|x|^{p-2}x,\quad p\gt 1,\] can be investigated via oscillatory properties of a certain associated second order linear ...
Ondřej Došlý
doaj
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
A note on the existence of solutions with prescribed asymptotic behavior for half-linear ordinary differential equations [PDF]
The half-linear differential equation (|u'|^{\alpha}{\rm sgn} u')' = \alpha(\lambda^{\alpha+ 1} + b(t))|u|^{\alpha}{\rm sgn} u, \quad t \geq t_0, is considered, where $\alpha$ and $\lambda$ are positive constants and $b(t)$ is a real-valued ...
Manabu Naito
doaj +1 more source
Oscillation criteria for second-order half-linear differential equations
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources

