Results 81 to 90 of about 1,460,019 (255)

Oscillation Criteria Enhanced for Advanced Half‐Linear Dynamic Equations

Journal of Mathematics
The purpose of this study is to develop new iterative oscillation criteria for second‐order half‐linear advanced dynamic equations. These findings improve and extend recently established criteria for the same equation by several authors as well as encompass the existing classical criteria for associated ordinary dynamic equations.
Taher S. Hassan, Elmetwally M. Elabbasy, Naveed Iqbal, Akbar Ali, Khudhayr A. Rashedi, Amir Abdel Menaem   +5 more
openaire   +2 more sources

Oscillations of half-linear second order differential equations

Hiroshima Mathematical Journal, 1995
Let \(\varphi:\mathbb{R}\to\mathbb{R}\) be defined by \(\varphi(s)=|s|^{p-2}s\), with \(p>1\) a fixed number. We extend Sturm's comparison theorem of the linear differential equation \[ {\textstyle {\frac{d}{dt}}} [r(t)u'(t)]+ c(t)u(t)=0 \] to the nonlinear differential equation \[ {\textstyle {\frac{d}{dt}}} \{r(t)\varphi(u'(t))\}+ c(t)\varphi(u(t))=0,
Li, Horng Jaan, Yeh, Cheh Chih
openaire   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

A Riccati technique for proving oscillation of a half-linear equation

Electronic Journal of Differential Equations, 2008
In this paper we study the oscillation of solutions to the half-linear differential equation $$ (r(t)|y'|^{p-1}hbox{sgn} y)'+c(t)|y|^{p-1}hbox{sgn} y=0, $$ under the assumptions $int^infty r^{1/(1-p)}(s),ds0$, $p>1$.
Pavel Rehak
doaj  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Existence of non-oscillatory solutions for second-order advanced half-linear differential equations

Electronic Journal of Differential Equations, 2013
In this article, we establish the necessary and sufficient conditions for existence of non-oscillatory solutions for the second-order advanced half-linear differential equation $$ ig(r(t)|x'(t)|^{alpha-1}x'(t)ig)'+p(t)|x(h(t)ig)|^{alpha-1}x(h(t))=0,
Aijun Cheng, Zhiting Xu
doaj  

Comparison theorems for oscillation and non-oscillation of perturbed Euler type equations [PDF]

Opuscula Mathematica
The aim of this paper is to present two comparison theorems. These results enable to describe the oscillation behavior of second order Euler type half-linear differential equations with perturbations in both terms using previously obtained oscillation ...
Petr Hasil, Jiřina Šišoláková, Michal Veselý   +2 more
doaj   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source