In all three domains of life, organisms use nonspecific DNA-binding proteins to compact and organize the genome as well as to regulate transcription on a global scale.
Keely A. Dulmage +2 more
doaj +1 more source
The crystal structure of Haloferax volcanii proliferating cell nuclear antigen reveals unique surface charge characteristics due to halophilic adaptation [PDF]
Background: The high intracellular salt concentration re quired to maintain a halophilic lifestyle poses challenges to haloarchaeal proteins that must stay soluble, stable and functional in this extreme environment.
Bunting, KA +3 more
core +2 more sources
Characterization of the mechanism of prolonged adaptation to osmotic stress of Jeotgalibacillus malaysiensis via genome and transcriptome sequencing analyses [PDF]
Jeotgalibacillus malaysiensis, a moderate halophilic bacterium isolated from a pelagic area, can endure higher concentrations of sodium chloride (NaCl) than other Jeotgalibacillus type strains.
Chan, K. G. +6 more
core +5 more sources
Archaeal S-layer glycoproteins: post-translational modification in the face of extremes [PDF]
Corresponding to the sole or basic component of the surface (S)-layer surrounding the archaeal cell in most known cases, S-layer glycoproteins are in direct contact with the harsh environments that characterize niches where Archaea can thrive ...
Jerry Eichler, Lina Kandiba
core +2 more sources
Bacterioopsin-Mediated Regulation of Bacterioruberin Biosynthesis in Halobacterium salinarum [PDF]
ABSTRACT Integral membrane protein complexes consisting of proteins and small molecules that act as cofactors have important functions in all organisms. To form functional complexes, cofactor biosynthesis must be coordinated with the production of corresponding apoproteins. To examine this coordination, we study bacteriorhodopsin
Antoinette M, Dummer +5 more
openaire +2 more sources
Structural conservation of chemotaxis machinery across Archaea and Bacteria [PDF]
Chemotaxis allows cells to sense and respond to their environment. In Bacteria, stimuli are detected by arrays of chemoreceptors that relay the signal to a two-component regulatory system.
Briegel, Ariane +5 more
core +3 more sources
Large scale physiological readjustment during growth enables rapid, comprehensive and inexpensive systems analysis [PDF]
Background Rapidly characterizing the operational interrelationships among all genes in a given organism is a critical bottleneck to significantly advancing our understanding of thousands of newly sequenced microbial and eukaryotic species.
Amardeep Kaur +15 more
core +3 more sources
Protein acetylation in archaea, bacteria, and eukaryotes [PDF]
Proteins can be acetylated at the alpha-amino group of the N-terminal amino acid (methionine or the penultimate amino acid after methionine removal) or at the epsilon-amino group of internal lysines.
Lainio, Jarmo +1 more
core +1 more source
Collective exchange processes reveal an active site proton cage in bacteriorhodopsin [PDF]
Proton translocation across membranes is vital to all kingdoms of life. Mechanistically, it relies on characteristic proton flows and modifications of hydrogen bonding patterns, termed protonation dynamics, which can be directly observed by fast magic ...
Brünig, Florian N. +5 more
core +1 more source
Genotypic and Lipid Analyses of Strains From the Archaeal Genus Halorubrum Reveal Insights Into Their Taxonomy, Divergence, and Population Structure [PDF]
To gain a better understanding of how divergence occurs, and how taxonomy can benefit from studying natural populations, we isolated and examined 25 closely related Halorubrum strains obtained from different hypersaline communities and compared them to ...
Corral Villa, Paulina +4 more
core +1 more source

