Results 81 to 90 of about 5,644 (180)

A comparative genomics perspective on the genetic content of the alkaliphilic haloarchaeon Natrialba magadii ATCC 43099T [PDF]

, 2012
BACKGROUND: Natrialba magadii is an aerobic chemoorganotrophic member of the Euryarchaeota and is a dual extremophile requiring alkaline conditions and hypersalinity for optimal growth. The genome sequence of Nab.
Diego E Sastre, Friedhelm Pfeiffer, Jean F Challacombe, John C Detter, Julie A Maupin-Furlow, Karen W Davenport, Lynne A Goodwin, María I Giménez, Nikos Kyrpides, Roberto A Paggi, Rosana E DeCastro, Roxanne Tapia, Samuel Pitluck, Shivakumara Siddaramappa, Susan Lucas, Tanja Woyke   +15 more
core   +2 more sources

Nanobubble Contrast Enhanced Ultrasound Imaging: A Review

WIREs Nanomedicine and Nanobiotechnology, Volume 16, Issue 6, November/December 2024.
(A) Numerous nanobubble (NB; ~100–500 nm diameter) formulations have been studied for imaging applications. Most agents are (i) stabilized with a protein, polymer, or lipid shell. Several formulations have also been (ii) decorated with fluorescent labeling or (iii) functionalized with epitopes targeting overexpressed biomarkers on diseased tissue.
Dana Wegierak, Pinunta Nittayacharn, Michaela B. Cooley, Felipe M. Berg, Theresa Kosmides, Dorian Durig, Michael C. Kolios, Agata A. Exner   +7 more
wiley   +1 more source

Genome‐Scale Metabolic Modeling of Halomonas elongata 153B Explains Polyhydroxyalkanoate and Ectoine Biosynthesis in Hypersaline Environments

Biotechnology Journal, Volume 19, Issue 10, October 2024.
Graphical Abstract and Lay Summary We constructed and validated a genome‐scale metabolic model for Halomonas elongata, revealing key metabolic changes during ectoine and PHA biosynthesis, including reduced oxidative phosphorylation and enhanced precursor production.
Blaise Manga Enuh, Pınar Aytar Çelik, Claudio Angione   +2 more
wiley   +1 more source

A Non‐Discriminating Aspartyl‐tRNA Synthetase fromHalobacterium salinarum [PDF]

RNA Biology, 2006
The tRNA-dependent transamidation pathway is the essential route for Asn-tRNA(Asn) formation in organisms that lack an asparaginyl-tRNA synthetase. This pathway relies on a nondiscriminating aspartyl-tRNA synthetase (ND-AspRS encoded by aspS), an enzyme with relaxed tRNA specificity, to form Asp-tRNA(Asn).
Alexander Machado, Cardoso, Carla, Polycarpo, Orlando Bonifácio, Martins, Dieter, Söll   +3 more
openaire   +2 more sources

Evolution and variation in amide aminoacyl‐tRNA synthesis

IUBMB Life, Volume 76, Issue 8, Page 505-522, August 2024.
Abstract The amide proteogenic amino acids, asparagine and glutamine, are two of the twenty amino acids used in translation by all known life. The aminoacyl‐tRNA synthetases for asparagine and glutamine, asparaginyl‐tRNA synthetase and glutaminyl tRNA synthetase, evolved after the split in the last universal common ancestor of modern organisms.
Alexander M. Lewis, Trevor Fallon, Georgia A. Dittemore, Kelly Sheppard   +3 more
wiley   +1 more source

AglM and VNG1048G, Two Haloarchaeal UDP-Glucose Dehydrogenases, Show Different Salt-Related Behaviors

Life, 2016
Haloferax volcanii AglM and Halobacterium salinarum VNG1048G are UDP-glucose dehydrogenases involved in N-glycosylation in each species. Despite sharing >60% sequence identity and the ability of VNG1048G to functionally replace AglM in vivo, these ...
Lina Kandiba, Jerry Eichler
doaj   +1 more source

Identification and codon reading properties of 5-cyanomethyl uridine, a new modified nucleoside found in the anticodon wobble position of mutant haloarchaeal isoleucine tRNAs [PDF]

, 2013
Most archaea and bacteria use a modified C in the anticodon wobble position of isoleucine tRNA to base pair with A but not with G of the mRNA. This allows the tRNA to read the isoleucine codon AUA without also reading the methionine codon AUG.
Babu, I. Ramesh, Blum, Paul, Chan, Tsz Yan Clement, Dedon, Peter C., Koehrer, Caroline, Kuwahara, Masayasu, Liu, Yuchen, Mandal, Debabrata, Rajbhandary, Uttam L., Soll, Dieter, Su, Dan   +10 more
core   +1 more source

Transmembrane proteins—Different anchoring systems

Proteins: Structure, Function, and Bioinformatics, Volume 92, Issue 5, Page 593-609, May 2024.
Abstract Transmembrane proteins are active in amphipathic environments. To stabilize the protein in such surrounding the exposure of hydrophobic residues on the protein surface is required. Transmembrane proteins are responsible for the transport of various molecules. Therefore, they often represent structures in the form of channels.
Irena Roterman, Katarzyna Stapor, Leszek Konieczny   +2 more
wiley   +1 more source

Extracts from Microalgae and Archaea from the Andalusian Coast: A Potential Source of Antiproliferative, Antioxidant, and Preventive Compounds

Journal of Marine Science and Engineering
Marine and extreme environments harbor a huge diversity of microorganisms able to produce new bioactive metabolites with beneficial health effects. In this study, ethanol, aqueous, methanol, and acetone extracts and protein hydrolysates were obtained ...
Cristina Luque, Gloria Perazzoli, Patricia Gómez-Villegas, Javier Vigara, Rosario Martínez, Alejandro García-Beltrán, Jesús M. Porres, Jose Prados, Rosa León, Consolación Melguizo   +9 more
doaj   +1 more source

Morphology of the archaellar motor and associated cytoplasmic cone in Thermococcus kodakaraensis [PDF]

, 2017
Archaeal swimming motility is driven by archaella: rotary motors attached to long extracellular filaments. The structure of these motors, and particularly how they are anchored in the absence of a peptidoglycan cell wall, is unknown.
Briegel, A., Chang, Y.-W., Ghosal, D., Gunsalus, R.P., Huang, A.N., Jensen, G.J., Kenny, D., Kim, K.W., Kjær, A., Loo, R.R., Nguyen, H.H., Ogorzalek, l.R., Oikonomou, C.M.   +12 more
core   +2 more sources