Results 81 to 90 of about 5,583 (160)

Controlled in meso phase crystallization--a method for the structural investigation of membrane proteins.

open access: yesPLoS ONE, 2012
We investigated in meso crystallization of membrane proteins to develop a fast screening technology which combines features of the well established classical vapor diffusion experiment with the batch meso phase crystallization, but without premixing of ...
Jan Kubicek   +5 more
doaj   +1 more source

Assessment of methods for evaluating structural stability of cell envelope fragments in hypersaline brines as biosignatures of ancient microbial life

open access: yesScientific Reports
The study of biomolecular stability of proteins and lipids in extreme saline environments is critical for understanding the preservation of potential microbial biosignatures of ancient life on Earth and other planetary bodies, including Mars.
Lucas Bourmancé   +3 more
doaj   +1 more source

Microbial model of Halobacterium salinarum for screening inhibitors of sterol biosynthesis

open access: yesАнтибиотики и Химиотерапия, 2020
A highly effective and simple microbial test system for screening inhibitors of sterol biosynthesis (ISB) is described. The system is based on cultivation of the bacterial strain Halobacterium salinarum (former Halobacterium halobium), that possesses ...
A. S. Trenin
doaj  

The Biosynthesis of the Thiazole Moiety of Thiamin in the Archaeon Halobacterium salinarum.

open access: yesJournal of nutritional science and vitaminology, 2015
The biosynthetic pathways of the thiazole moiety of thiamin were studied in the archaeon Halobacterium salinarum. Thiamin is generated by the union of 4-amino-5-hydroxymethyl-2-methylpyrimidine (pyrimidine) and 5-(2-hydroxyethyl)-4-methylthiazole (thiazole). The biosynthesis of thiazole is different in facultative anaerobes, aerobes and eukaryotes.
HAYASHI, Maria   +3 more
openaire   +2 more sources

New Biologically Active Compounds in the Series of 3-(indol-1-yl)-, 3-(N-aminoaryl)-, and 3-(S-thioaryl)Maleimide Derivatives

open access: yesАнтибиотики и Химиотерапия, 2020
Novel compounds among 3,4-disubstituted maleimlde derivatives that reveal a pronounced antimicrobial activity in vitro against Gram-positive bacteria, yeast Candida albicans, and fungi Aspergillus niger were obtained through total chemical synthesis. All
S. A. Lakatosh   +5 more
doaj  

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