Results 111 to 120 of about 5,137 (188)

Chromatin and gene regulation in archaea

Molecular Microbiology, Volume 123, Issue 3, Page 218-231, March 2025.
Recent data from diverse archaea with different repertoires of nucleoid‐associated proteins show a common genome‐wide chromatin organisation where chromatin maintains access to gene promoters independently of transcription activity. Abstract The chromatinisation of DNA by nucleoid‐associated proteins (NAPs) in archaea ‘formats’ the genome structure in ...
Fabian Blombach, Finn Werner
wiley   +1 more source

Regulation of DNA Topology in Archaea: State of the Art and Perspectives

Molecular Microbiology, Volume 123, Issue 3, Page 245-264, March 2025.
DNA topoisomerases are ubiquitous enzymes that play a crucial role in regulating DNA supercoiling which affects fundamental biological processes involving DNA. In this review, we summarize the current understanding of regulation of supercoiling by DNA topoisomerases in the third domain of life, the Archaea, with a particular focus on three key model ...
Paul Villain, Tamara Basta
wiley   +1 more source

Ribosome surface properties may impose limits on the nature of the cytoplasmic proteome

eLife, 2017
Much of the molecular motion in the cytoplasm is diffusive, which possibly limits the tempo of processes. We studied the dependence of protein mobility on protein surface properties and ionic strength.
Paul E Schavemaker, Wojciech M Śmigiel, Bert Poolman   +2 more
doaj   +1 more source

HPClas: A data‐driven approach for identifying halophilic proteins based on catBoost

mLife, Volume 3, Issue 4, Page 515-526, December 2024.
Abstract Halophilic proteins possess unique structural properties and show high stability under extreme conditions. This distinct characteristic makes them invaluable for application in various aspects such as bioenergy, pharmaceuticals, environmental clean‐up, and energy production.
Shantong Hu, Xiaoyu Wang, Zhikang Wang, Menghan Jiang, Shihui Wang, Wenya Wang, Jiangning Song, Guimin Zhang   +7 more
wiley   +1 more source

Identification and codon reading properties of 5-cyanomethyl uridine, a new modified nucleoside found in the anticodon wobble position of mutant haloarchaeal isoleucine tRNAs [PDF]

, 2013
Most archaea and bacteria use a modified C in the anticodon wobble position of isoleucine tRNA to base pair with A but not with G of the mRNA. This allows the tRNA to read the isoleucine codon AUA without also reading the methionine codon AUG.
Babu, I. Ramesh, Blum, Paul, Chan, Tsz Yan Clement, Dedon, Peter C., Koehrer, Caroline, Kuwahara, Masayasu, Liu, Yuchen, Mandal, Debabrata, Rajbhandary, Uttam L., Soll, Dieter, Su, Dan   +10 more
core   +1 more source

Understanding the tolerance of halophilic archaea to stress landscapes

Environmental Microbiology Reports, Volume 16, Issue 6, December 2024.
The tolerance responses of nine Haloarchaea species were analysed under 70 different conditions, including various salinities, temperatures, oxidative stress and the presence of metals. In general, all characterised species tolerated heavy metals, with a particularly striking tolerance to lithium. These results highlight the relevance of Haloarchaea in
Laura Matarredona, Basilio Zafrilla, Mónica Camacho, María‐José Bonete, Julia Esclapez   +4 more
wiley   +1 more source

Analysis of multiple haloarchaeal genomes suggests that the quinone-dependent respiratory nitric oxide reductase is an important source of nitrous oxide in hypersaline environments [PDF]

, 2017
Microorganisms, including Bacteria and Archaea, play a key role in denitrification, which is the major mechanism by which fixed nitrogen returns to the atmosphere from soil and water.
Al-Attar, Altschul, Arnold, Becker, Bell, Bellanger, Bergaust, Berks, Biasini, Bonete, Bordoli, Braker, Büsch, Carr, Casciotti, Cramm, Cramm, Edgar, Esclapez, Falk, Fernández-Gómez, Fukuchi, Gasteiger, Gómez-Hernández, Han, Hendriks, Heylen, Hino, Hochstein, Ichiki, Inatomi, Kumar, Lledó, Longo, Mancinelli, Martínez-Espinosa, Martínez-Espinosa, Martínez-Espinosa, Matsumoto, Mattar, Mau, Nájera-Fernández, Offre, Oren, Oren, Oren, Ortega, Poole, Reed, Richardson, Salomonsson, Scharf, Shiro, Slater, Spiro, Suharti, Terasaka, Thorndycroft, Tindall, Torregrosa-Crespo, Vries, Völkl, Watmough, Yoshimatsu, Zumft, Zumft, Zumft, Zumft   +67 more
core   +3 more sources

tsRNAs: A Prospective, Effective Therapeutic Intervention for Neurodegenerative Diseases

CNS Neuroscience &Therapeutics, Volume 30, Issue 12, December 2024.
Transfer RNA‐derived small RNAs (tsRNAs) are generated through the cleavage of transfer RNAs. tsRNAs modulate gene expression through transcriptional and translational mechanisms. tsRNAs are implicated in the pathogenesis of neurodegenerative disorders.
Tianqi Li, Hui Zhen, Weiwei Wu, Fengtang Yang, Zhonghong Cao   +4 more
wiley   +1 more source

N-glycosylation in the thermoacidophilic archaeon Sulfolobus acidocaldarius involves a short dolichol pyrophosphate carrier [PDF]

, 2016
N-glycosylation is a post-translational modification that occurs across evolution. In the thermoacidophilic archaea Sulfolobus acidocaldarius, glycoproteins are modified by an N-linked tribranched hexasaccharide reminiscent of the N-glycans assembled in ...
Abu-Qarn, Aebi, Albers, Bligh, Brock, Burda, Calo, Chang, Cohen-Rosenzweig, Eichler, Guan, Guan, Guan, Gulik, Hartley, Hartmann, Jarrell, Jones, Kaminski, Kandiba, Kelleher, Kuntz, Larkin, Lechner, Lehrman, Mescher, Meyer, Meyer, Meyer, Nothaft, Palmieri, Peyfoon, Shams-Eldin, Swiezewska, Szymanski, Taguchi, Wagner, Weerapana, Zahringer   +38 more
core   +3 more sources

Insights into gene expression changes under conditions that facilitate horizontal gene transfer (mating) of a model archaeon

Scientific Reports, 2020
Horizontal gene transfer is a means by which bacteria, archaea, and eukaryotes are able to trade DNA within and between species. While there are a variety of mechanisms through which this genetic exchange can take place, one means prevalent in the ...
Andrea M. Makkay, Artemis S. Louyakis, Nikhil Ram-Mohan, Uri Gophna, J. Peter Gogarten, R. Thane Papke   +5 more
doaj   +1 more source