Results 51 to 60 of about 11,578 (241)
Molecules, 2021 The 3D structure and surface characteristics of proteins and peptides are crucial for interactions with receptors or ligands and can be modified to some extent to modulate their biological roles and pharmacological activities. The introduction of halogen
Mario Mardirossian +7 more
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Molecules, 2001 The Baylis-Hillman reactions of various aryl aldehydes with methyl vinyl ketone at temperatures below -20oC using Lewis acids such as titanium (IV) chloride, boron (III) chloride or zirconium (IV) chloride in the presence of a catalytic amount of ...
Shi-Cong Cui, Jian-Kang Jiang, Min Shi
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Enzymatic Bromocyclization of α‐ and γ‐Allenols by Chloroperoxidase from Curvularia inaequalis
ChemistryOpen, 2022 Vanadate‐dependent chloroperoxidase from Curvularia inaequalis catalyzes 5‐endo‐trig bromocyclizations of α‐allenols to produce valuable halofunctionalized furans as versatile synthetic building blocks. In contrast to other haloperoxidases, also the more
Janne M. Naapuri +3 more
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Halogenation of polypnictogen ligand complexes [PDF]
, 2023 After that a previous investigation from our group demonstrated that the iodination and the “classical” oxidation of En ligand complexes can afford different results and are therefore being considered as complementary tools for the synthesis of new ...
Garbagnati, Anna
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Late‐Stage Functionalization of Peptides on the Solid Phase
Angewandte Chemie International Edition, EarlyView.Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner +2 more
wiley +1 more source
Decarbonylative Halogenation by a Vanadium Complex
, 2016 Metal-catalyzed halogenation of the C–H bond and decarbonylation of aldehyde are conventionally done in nature. However, metal-mediated decarbonylative halogenation is unknown.
Rameezul Haque (1980220) +3 more
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Amine Directed Palladium Catalyzed C‐H Halogenation of Phenylalanine Derivatives
, 2021 International audienceAn efficient primary amine-directed palladium catalyzed C-H halogenation (X = I, Br, Cl) of phenylalanine derivatives is reported on a range of quaternary amino acid (AA) derivatives thanks to suited conditions employing ...
Coufourier, Sébastien +7 more
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Chemistry – A European Journal, EarlyView.The synthesis of 2‐methyl propellane and its conversion to various 1,2‐ and 1,2,3‐di‐ and trisubstituted bicyclopentanes is reported. Abstract Bicyclo[1.1.1]pentanes (BCPs) have emerged as isosteric replacements for mono‐ and para‐substituted benzene rings in medicinal and materials applications, involving substitution at the BCP bridgehead (1,3 ...
Sean R. Verschaeve +4 more
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Halogenation. Part I. Iodination.
, 1926 Halogenation.
DATTATREYA ANANT KULKARNI +1 more
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Chemistry – A European Journal, EarlyView.Over the past decade, the interest in azetidines has continuously risen, by virtue of their highly appealing pharmaceutical properties. Monocyclic, spirocyclic, and bridged azetidines can be accessed by leveraging 1‐azabicyclo[1.1.0]butanes as precursors.
Yuri Gelato +3 more
wiley +1 more source