Results 31 to 40 of about 12,869 (241)
Molecules, 2021 A series of halogenated 1,5-diarylimidazole compounds were synthesized and their inhibitory effects on LPS-induced PGE2 production in RAW 264.7 cells were evaluated.
Zunhua Yang +4 more
doaj +1 more source
Synthesis and spectrometric study of some nucleophilic reactions of the antiepileptic molecule; 5,5-diphenyl imidazolidine-2,4-dione. [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2018 New reaction routs were performed for the compound 5,5-diphenyl 2,4-imidazolidinedione (I) to give derivatives (II – VII). These reactions include acylation, halogenation, reduction, and nucleophilic substitutions. Most of the derivatives showed variable
Saadi M. D. Al-Nuzal +2 more
doaj +1 more source
Metals, 2018 The present study focuses on the pyrolysis of discarded smartphone displays in order to investigate if a halogenation and volatilization of indium is possible without a supplementary halogenation agent.
Benedikt Flerus +4 more
doaj +1 more source
Chemical Reviews, 2016 The halogen bond occurs when there is evidence of a net attractive interaction between an electrophilic region associated with a halogen atom in a molecular entity and a nucleophilic region in another, or the same, molecular entity. In this fairly extensive review, after a brief history of the interaction, we will provide the reader with a snapshot of ...
Cavallo, Gabriella +7 more
openaire +2 more sources
Frontiers in Chemistry, 2018 In this work we present the first computational study on the hectochlorin biosynthesis enzyme HctB, which is a unique three-domain halogenase that activates non-amino acid moieties tethered to an acyl-carrier, and as such may have biotechnological ...
Amy Timmins +5 more
doaj +1 more source
Halogen⋯halogen contra C–H⋯halogen interactions
CrystEngComm, 2014 Pressure affects the competition between C–H⋯X hydrogen bonds and X⋯X halogen⋯halogen interactions. In bromomethane, CH3Br, pressure changes the molecular arrangement of the two solid-state phases of this compound: low-pressure phase α is dominated by halogen⋯halogen interactions, whereas above 1.5 GPa the β phase is governed by C–H⋯halogen bonds.
Marcin Podsiadło +2 more
openaire +2 more sources
Halogenation effect on physicochemical properties of Ti3C2 MXenes
JPhys Materials, 2023 Halogenated MXenes have been experimentally demonstrated to be promising two-dimensional materials for a wide range of applicability. However, their physicochemical properties are largely unknown at the atomic level.
Seyedeh Alieh Kazemi +6 more
doaj +1 more source
‐3‐Halogenation of its Native Substrate [PDF]
, 2021 Non-heme iron/ α -ketoglutarate dependent halogenases acting on freestanding substrates catalyze the regio- and stereoselective halogenation of inactivated C(sp 3 )-H bonds.
Takahiro Hayashi +14 more
core +1 more source
Unified Synthesis of Unconventional α-Polyhalogenated Amines Through Hydroaminoalkylation. [PDF]
Angew Chem Int Ed EnglA unified, redox‐neutral method that transforms alkenes and alkynes into α‐polyhalomethyl amines using stable hemiaminal reagents is reported. This approach enables access to CF3, CF2H, CF2Cl, and CFClH motifs, expanding halogenated amine space with broad substrate scope, functional group tolerance, and applicability to late‐stage modification of drug ...
Hofmeister AK +9 more
europepmc +2 more sources
Halogenation of Pharmaceuticals Is an Impediment to Ready Biodegradability
, 2023 International audienceFor pharmacological reasons many active organic pharmaceutical substances (AOPSs) are singly or multiply halogenated. Halogenation can confer optimised steric fitting of an AOPS to its molecular receptor; moreover, by increasing the
Le Roux, Julien +5 more
core +1 more source