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Acute antipsychotic-induced abnormal involuntary movements restricted to the platysma.
Indian J PsychiatryMendhekar D, Andrade C.
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Haloperidol and Reduced Haloperidol in
Journal of Clinical Psychopharmacology, 1992A total of 18 outpatients (17 male, 1 female) ranging in age from 36-66 years old were on a constant dosage of haloperidol in equally divided doses at 9:00 a.m. and 9:00 p.m. for at least 1 month. DSM-III-R diagnoses included schizophrenia (N = 9), schizoaffective disorder (N = 3), bipolar disorder (N = 4), organic mental disorder (N = 1), and ...
Michael A. Kuskowski +6 more
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Quantification of Reduced Haloperidol and Haloperidol by Radioimmunoassay
Journal of Immunoassay, 1985A radioimmunoassay for reduced haloperidol and haloperidol has been developed by using a simple derivatization-separation step prior to assay with an antibody cospecific for both compounds. The detection limit of the assay is less than 25 pg and shows no cross reactivity to other metabolites.
C. A. Harrington +2 more
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On the metabolism of haloperidol
Xenobiotica, 19931. p-Fluorobenzoyl-propionic acid, 4-(4-chlorophenyl)-4-hydroxy-piperidine, and reduced haloperidol were confirmed as metabolites of haloperidol. Their formation was catalysed by hepatic microsomes and was NADPH dependent. 2. The pyridinium metabolite of haloperidol (HP+) was identified.
Jim Fang, J W Gorrod
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Annals of Clinical Psychiatry, 2005
Haloperidol was synthesized on the 11th of February 1958 at the Janssen Laboratories, in Belgium. Soon after its synthesis and animal studies, which suggested to Paul Janssen and his colleagues that this butyrophenone drug would be of great interest as its action was similar but much more powerful than that of chlorpromazine, haloperidol was ...
Bernard Granger, Simona Albu
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Haloperidol was synthesized on the 11th of February 1958 at the Janssen Laboratories, in Belgium. Soon after its synthesis and animal studies, which suggested to Paul Janssen and his colleagues that this butyrophenone drug would be of great interest as its action was similar but much more powerful than that of chlorpromazine, haloperidol was ...
Bernard Granger, Simona Albu
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Psychopharmacology, 1986
Plasma concentrations of haloperidol and its reduced metabolite (reduced haloperidol) were investigated in cigarette smokers (N = 23) and nonsmokers (N = 27). Steady-state plasma concentrations were obtained 12 h post bedtime dose. Haloperidol and reduced haloperidol concentrations were determined by RIA.
Charles A. Harrington +5 more
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Plasma concentrations of haloperidol and its reduced metabolite (reduced haloperidol) were investigated in cigarette smokers (N = 23) and nonsmokers (N = 27). Steady-state plasma concentrations were obtained 12 h post bedtime dose. Haloperidol and reduced haloperidol concentrations were determined by RIA.
Charles A. Harrington +5 more
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Reduced haloperidol/haloperidol ratios after oral haloperidol and decanoate administration in schizophrenics [PDF]
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 1993 Abstract 1. Haloperidol and reduced haloperidol plasma concentrations were measured in thirteen stable schizophrenic patients that received both oral haloperidol and haloperidol decanoate. 2. Significant correlations between reduced haloperidol/haloperidol ratios from oral haloperidol and haloperidol decanoate occurred at week two and week 16 ...
Lin Shih-Ku +8 more
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