Advanced Science, EarlyView.The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt +16 more
wiley +1 more source
THE ROLE OF FOREIGN LANGUAGE TEACHERS IN DEVELOPING STUDENTS’ INTERCULTURAL COMMUNICATION SKILLS [PDF]
Journal of Languages for Specific Purposes, 2014 By now it is well-known that the role of modern education is to equip students with several types of competences necessary for their future personal and professional life.
Andrea Hamburg
doaj
Therapeutic Gene Editing of APOE4 in Sporadic Alzheimer's Disease via Prime Editor 7
Advanced Science, EarlyView.Prime Editor 7‐mediated conversion of APOE4 to APOE3 alleviates Alzheimer's disease‐associated pathology in AD mouse models and patient‐derived neurons and improves cognitive performance in vivo, supporting therapeutic genome editing as a promising strategy for APOE4‐associated neurodegeneration.
Yunkyung Kim +16 more
wiley +1 more source
AMELA ĆURKOVIĆ / ALMINA LISIČIĆ-HEDŽIĆ: ERFOLGREICHE GESCHÄFTS-KORRESPONDENZ AUF DEUTSCH, LEHR- UND ÜBUNGSBUCH [AMELA ĆURKOVIĆ / ALMINA LISIČIĆ-HEDŽIĆ: SUCCESFUL BUSINESS CORRESPONDENCE IN GERMAN, TEXT- AND EXERCISEBOOK] [PDF]
Journal of Languages for Specific PurposesBook ...
Andrea Hamburg
doaj
Advanced Science, EarlyView.Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries +25 more
wiley +1 more source
BURÇAK ÇAĞLA GARIPAĞAOĞLU (Ed.) NEED FOR A NEW PARADIGM IN EDUCATION. FROM THE NEWTONIAN PARADIGM TO THE QUANTUM PARADIGM [PDF]
Journal of Languages for Specific PurposesBook ...
Andrea Hamburg
doaj
Advanced Science, EarlyView.Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl +20 more
wiley +1 more source
DIGITALE LEHR- UND LERNMITTEL ZWISCHEN ANZIEHUNGSKRAFT UND WIRKSAMKEIT / English Title: DIGITAL TEACHING AND LEARNING TOOLS BETWEEN ATTRACTIVITY AND EFFECTIVENESS [PDF]
Journal of Languages for Specific PurposesIn the last decades all over the world emerged different trends and approaches in education in general, thus in teaching foreign languages too. New times are likely to need also new teaching methods, young people of this millennium put teachers in front ...
Andrea Hamburg
doaj
Chemical‐Biological Fixation for Enhanced Bone Augmentation in Guided Bone Regeneration
Advanced Science, EarlyView.M2N2ACa is an innovative injectable thermoresponsive barrier membrane adhesive to achieve reliable bone graft fixation. It provides strong wet adhesion and promotes the bio‐stabilization mediated by coagulation through controlled calcium release. This dual‐fixation strategy combines external chemical fixation and internal biological fixation via clot ...
Yu‐zhu Wang +13 more
wiley +1 more source
Dispersion‐Clamped Crystalline Supramolecular Columnar π‐Stacks of Adamantyl‐Substituted Pyrenes
Angewandte Chemie, EarlyView.Can neutral hydrocarbon π‐systems be forced into perfectly aligned cofacial stacks in crystals? An adamantyl‐decorated pyrene derivative crystallizes into rare translationally zero‐offset π‐columns, producing a short π–π distance below 3.3 Å and a large color shift arising from frontier crystal orbital (FCO) formation. ABSTRACT Despite their importance
Kazutaka Shoyama
wiley +2 more sources