Results 81 to 90 of about 19,908 (281)
Giant reverse transcriptase-encoding transposable elements at telomeres [PDF]
, 2017 Author Posting. © The Author(s), 2017. This is the author's version of the work. It is posted here by permission of Oxford University Press for personal use, not for redistribution.
Arkhipova, Irina R. +2 more
core +1 more source
Factors determining chromosomal localization of transposable elements in plants
Plant Biology, EarlyView.We review transposon chromosomal niches, and the functional consequences of their specific chromosomal localization in plants. Abstract Transposable elements (TEs) constitute a significant part of plant genomes and shape their genomic landscape. While some TEs are ubiquitously dispersed, other elements specifically occupy discrete genomic loci.
E. Kejnovsky +3 more
wiley +1 more source
Meeting review : ESF workshop on "Impact of nucleic acid chemistry on gene function analysis: antisense, aptamers, ribozymes and RNAi" [PDF]
, 2008 The shortage of functional information compared to the abundance of sequence information characterizes today’s situation in functional genomics. For many years the knock-down of a gene’s product has been the most powerful way of analysing its function ...
Engels, Joachim W. (Prof. Dr.) +3 more
core
RNA: A publication of the RNA Society, 2012 Although the Hammerhead ribozyme (HHRz) has long been used as a model system in the field of ribozyme enzymology, several details of its mechanism are still not well understood.
Ward Wl, V. DeRose
semanticscholar +1 more source
Computational De Novo Design of Group II Introns Yields Highly Active Ribozymes
ChemBioChem, Volume 26, Issue 14, July 18, 2025.Group II Introns (G2Is) are large self‐splicing ribozymes with promising biotechnological applications. This study utilized RNA inverse folding to design three novel G2Is. The designed intron Arq.I2, an unexpectedly proficient ribozyme, self‐splices not only in vitro, but also in Escherichia coli cells.
Deni Szokoli +3 more
wiley +1 more source
The Structure, Function and Application of the Hammerhead Ribozyme [PDF]
European Journal of Biochemistry, 1997 The hammerhead ribozyme is one of the smallest ribozymes known and catalyses the site‐specific hydrolysis of a phosphodiester bond. This small ribozyme is of interest for two reasons. It offers a convenient system to study the structure/function relationship of a nucleotide sequence, and is a potential vehicle for the inhibition of gene expression. The
Fritz Eckstein +2 more
openaire +3 more sources
Lipid vesicles chaperone an encapsulated RNA aptamer. [PDF]
, 2018 The organization of molecules into cells is believed to have been critical for the emergence of living systems. Early protocells likely consisted of RNA functioning inside vesicles made of simple lipids.
Chen, Irene A +2 more
core +1 more source
Selective Nonenzymatic Formation of Biologically Common RNA Hairpins
Angewandte Chemie, Volume 137, Issue 5, January 27, 2025.Template‐free RNA loop‐closing ligation selectively generates RNA tetraloops that are prevalent in biology, as demonstrated by high‐throughput sequencing. Utilizing high‐yield overhang sequences enables the efficient assembly of functional RNAs. Abstract The prebiotic formation of RNA building blocks is well‐supported experimentally, yet the emergence ...
Long‐Fei Wu +5 more
wiley +2 more sources
RNA BiologySelf-cleaving ribozymes are versatile tools for synthetic biologists when it comes to controlling gene expression. Up to date, 12 different classes are known, and over the past decades more and more details about their structure, cleavage mechanisms and ...
Dennis Kläge +2 more
doaj +1 more source
Biology, 2021 A high pressure apparatus allowing one to study enzyme kinetics under pressure was used to study the self-cleavage activity of the avocado sunblotch viroid.
Hussein Kaddour +4 more
doaj +1 more source