Results 101 to 110 of about 254,338 (311)
Hantaviruses are rodent-borne viruses that cause severe disease in infected humans. In the New World, major hantaviruses include Andes virus (ANDV) and Sin Nombre virus (SNV) causing hantavirus pulmonary syndrome.
Rebecca L. Brocato +10 more
doaj +1 more source
A Mechanistic Model of rAAV Production in Synthetic Cell Lines
ABSTRACT The recombinant adeno‐associated virus (rAAV) is a widely used vector for gene therapy. Its manufacturing faces significant challenges in producing the large quantities of vectors needed for clinical applications and reducing empty particles.
Prahalad Srinivasan +5 more
wiley +1 more source
Kongratanapasert T, Kongsomros S, Arya N, et al. J Exp Pharmacol. 2023;15:13–26. Page 19, line two, the text “510.25 ± 329.37 and 2015.74 ± 708.53 μg/g” should read “510.25 ± 329.37 and 2015.74 ...
Kongratanapasert T +18 more
doaj
Nearly Fuchsian surface subgroups of finite covolume Kleinian groups
Let Gamma < PSL_2(C) be discrete, cofinite volume, and noncocompact. We prove that for all K > 1, there is a subgroup H < Gamma that is K-quasiconformally conjugate to a discrete cocompact subgroup of PSL_2(R).
Kahn, Jeremy, Wright, Alex
core
Nicotinamide Reverses the Warburg Effect in CHO Cell Culture
Abstract The Warburg effect, the preferential conversion of glucose‐derived pyruvat to lactate despite available oxygen, is a key feature of Chinese hamster ovary (CHO) cell culture. Lactate accumulation in recombinant protein‐producing cell culture is an inefficient usage of glucose, as well as being deleterious to cells.
James Morrissey +7 more
wiley +1 more source
The role of depressed metabolism in increased radio-resistance [PDF]
The results of experiments on hamsters and rats to determine physiological responses to various temperature conditions are presented. The experimental methods described are considered to be applicable to future mammalian experiments in space.
Musacchia, X. J.
core +1 more source
Laser Microirradiation of Chinese Hamster Cells at Wavelength 365 nm [PDF]
Cells of a V79 subline of the Chinese hamster were microirradiated at wavelength 365 nm in the presence of the psoralen derivative, trioxsalen. Microirradiation was accomplished by a pulsed argon laser microbeam either in anaphase or in interphase 3 hr ...
Berns, Michael W. +3 more
core
One‐Pot Synthesis of a Small Synthetic Ligand for Antibody Purification
One‐pot liquid‐phase synthesis of the synthetic ligand B1Al2A2 enables controllable ligand density and efficient capture of IgG and IgY with high recovery and purity, streamlining small‐ligand affinity purification workflows. ABSTRACT The development of synthetic affinity ligands offers a cost‐effective alternative to traditional biological ligands ...
Carolina Mota Natal +8 more
wiley +1 more source
Objective: Ibuprofen and L-carnitine have been demonstrated to provide radioprotective activity to the hamster against whole body sublethal irradiation.
Meryem Akpolat +4 more
doaj
Detergent Virus Inactivation in Chromatography Systems
ABSTRACT Detergent treatment is a widely utilized virus‐inactivation step in therapeutic protein manufacturing to safeguard products. Traditionally, this operation is performed in an incubation vessel in batch mode. In this investigation, a methodology was developed to enable virus inactivation via a post‐load, detergent‐containing wash within a bind ...
Kang Cai +6 more
wiley +1 more source

