Results 111 to 120 of about 162,987 (311)

Pharmacological Activities of Fingerroot Extract and Its Phytoconstituents Against SARS-CoV-2 Infection in Golden Syrian Hamsters [Corrigendum]

Journal of Experimental Pharmacology, 2023
Kongratanapasert T, Kongsomros S, Arya N, et al. J Exp Pharmacol. 2023;15:13–26. Page 19, line two, the text “510.25 ± 329.37 and 2015.74 ± 708.53 μg/g” should read “510.25 ± 329.37 and 2015.74 ...
Kongratanapasert T, Kongsomros S, Arya N, Sutummaporn K, Wiriyarat W, Akkhawattanangkul Y, Boonyarattanasoonthorn T, Asavapanumas N, Kanjanasirirat P, Suksatu A, Sa-ngiamsuntorn K, Borwornpinyo S, Vivithanaporn P, Chutipongtanate S, Hongeng S, Ongphiphadhanakul B, Thitithanyanont A, Khemawoot P, Sritara P   +18 more
doaj  

Next‐Generation Glutamine Synthetase Expression Vector for Therapeutic Protein Manufacturing Using CHO Cells

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The glutamine synthetase expression system is widely used for therapeutic protein biomanufacturing in Chinese hamster ovary (CHO) cells. Here, we present the design of an enhanced glutamine synthetase vector for generating CHOK1SV GS‐KO stable pools that produce recombinant proteins at multigram‐per‐liter levels. We first developed a synthetic
Yusuf B. Johari, Sophie J. Wensley, Malak A. Ammar, Avinash Srivastava, Changhavi Ragurajan, Jenish Patel, Natalie C. Elliott, Alice C. Hodgson‐Casson, Mariano Olivera Fedi, Michael Anbar, Peter M. O'Callaghan, Bernie Sweeney   +11 more
wiley   +1 more source

Hamster Neurula (after turning)

, 2020
Object: Microscopic slides (19)Platform: PathXLOrganism: Cricetus auratus (Hamster)Subject: Neurula (after turning)Orientation: Cross sectionStaining: SilverMagnification: 40xZ-stacks ...
E.A. (Elly) Langewis (6012872)
core   +1 more source

Feasibility Assessment of a Single‐pH Connected Polishing Train for Monoclonal Antibody Purification Using Mildly Acidic Protein A Elution and an Acidic‐Window Anion Exchange Membrane

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Monoclonal antibody downstream processing often requires multiple pH adjustments between Protein A capture and polishing steps. These adjustments increase process complexity and make direct unit‐operation connection more difficult. We evaluated a connected post‐capture polishing block operated at approximately pH 5.0 using mild‐pH Protein A ...
Takaki Aiso, Hiroshi Muto, Kyota Suzuki, Yumiko Masuda, Hirofumi Kakihara, Masashi Sonoyama   +5 more
wiley   +1 more source

Protective Effects of Ibuprofen and L-Carnitine Against Whole Body Gamma Irradiation-Induced Duodenal Mucosal Injury

Balkan Medical Journal, 2011
Objective: Ibuprofen and L-carnitine have been demonstrated to provide radioprotective activity to the hamster against whole body sublethal irradiation.
Meryem Akpolat, Yeter Topçu-Tarladaçalışır, Dikmen Dökmeci, Fatma Nesrin Turan, Mustafa Cem Uzal   +4 more
doaj  

Beschermingsplan hamster 2005-2010 [PDF]

, 2005
Alterra-Concept van het beschermingsplan hamster 2005-2010. De hamster is in het meest westelijke deel van het Europese verspreidingsgebied bedreigd. De kennis die in de afgelopen periode is opgedaan van de hamster en de maatregelen die in het veld zijn ...
Haye, M.J.J., la, Jansman, H.A.H.
core  

A Hybrid Mechanistic Model Capturing Lactate Run‐Away and Back‐Metabolism in Mammalian Cell Culture

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Mechanistic modeling is important in biopharmaceutical manufacturing by enabling in‐silico experimentation. However, developing a robust mechanistic model for mammalian cell culture remains challenging due to the complexity of the underlying bioprocesses.
Li Qin, James Savery, Matthew Cheeks, Suzanne S. Farid, Stephen Goldrick   +4 more
wiley   +1 more source

Batch‐to‐Batch Optimization of pH Shifts in CHO Bioreactor Operations

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Culture pH is an important operating parameter in CHO cell cultures producing mAb since it directly affects growth and specific productivity. Mathematical models can be used to optimize the magnitude and timing of pH shifts provided that they are robust to model errors.
Ali Ghodba, Zahra Negahban, Anne Richelle, Chris McCready, Valerie Ward, Luis Ricardez‐Sandoval, Hector Budman   +6 more
wiley   +1 more source

Amino acid analyses of hamster cecal contents.

, 2016
Amino acid analyses of hamster cecal contents.
Brintha Parasumanna Girinathan (3145011), Sterling Braun (3145008), Revathi Govind (159469), Jose Espinola Lopez (3145002), Apoorva Reddy Sirigireddy (3145005)   +4 more
core   +1 more source

Screening of bispecific antibodies during single cell cloning of recombinant Chinese hamster ovary cell lines to improve titer and product quality

Biotechnology Progress, EarlyView.
Abstract Development of therapeutic bispecific antibodies (BsAbs) poses significant manufacturability challenges associated with correct chain pairing and an increased diversity of impurities. Here we address this with a product quality assessment during cell line development (CLD), forgoing the need for genetic characterization during cell line ...
Molly Robinson, Jessica Willmott, Holly Corrigall, Daniela Lega, Joseph Stirling, Vithiya Vimalraj, Mitul Patel, Robyn Emmins   +7 more
wiley   +1 more source