Results 131 to 140 of about 115,928 (265)

Hsp70 diversification and repurposing across the tree of life: Lessons from the evolutionary and mechanistic trajectory of the Hsp70–Hsp110 chaperone system

open access: yesThe FEBS Journal, EarlyView.
Evolutionary and mechanistic divergence in the Hsp70–Hsp110 chaperone system. Prokaryotic Hsp70s probably diversified into multiple orthologues that cooperated with co‐chaperones such as JDPs and NEF, forming increasingly complex proteostasis networks.
Pierre Goloubinoff   +2 more
wiley   +1 more source

Innate Immune Activation Is a Strong Suppressor of CCL22 and Impedes Regulatory T Cell–Dendritic Cell Interaction

open access: yesImmunology, EarlyView.
During homeostasis, CCL22 is secreted by dendritic cells (DC), which mediate contacts between regulatory T cells (Treg) and DC to maintain immune balance. Activation of innate immunity via microbes or pattern recognition receptor (PRR) agonists induces the secretion of several soluble factors (e.g., type I and II interferons, IL‐10), which mediate ...
Ignazio Piseddu   +24 more
wiley   +1 more source

MICROTUBULES IN HAMSTER PLATELETS [PDF]

open access: yesThe Journal of Cell Biology, 1965
G B, Haydon, D A, Taylor
openaire   +2 more sources

Dual Beneficial Effects of Topical l‐Glutamine on Oral Mucositis in 5‐Fluorouracil‐Treated Mice

open access: yesJournal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Oral mucositis is a severe health and economic problem that occurs in about 40%–90% of patients undergoing cancer treatments. Systemic or topical application of l‐glutamine has been shown to improve mucosal healing and ameliorate oral mucositis (OM) symptoms according to clinical score systems.
Juliana Francisca Grossi Heleno   +7 more
wiley   +1 more source

Models of Oral Epithelial Dysplasia: A Systematic Review and Temporal Analysis

open access: yesJournal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Oral squamous cell carcinoma (OSCC) is the most common malignancy of the head and neck, associated with substantial morbidity and mortality worldwide. Oral epithelial dysplasia (OED) can precede OSCC, offering a critical window for preventive and therapeutic intervention.
Zilefac Brian Ngokwe   +4 more
wiley   +1 more source

Differences in Feeding Management of Pet Rabbits by Owners and Hobby Breeders and Their Impact on Animals' Health: A Survey

open access: yesJournal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Over the last decades, the population of pet rabbits in Europe has increased significantly, but to date studies into feeding management of these species have been mainly conducted in production animals. This study aimed to evaluate the feeding practices of both pet rabbit owners and hobby breeders in Germany and how these may affect animal ...
Federica Sportelli   +5 more
wiley   +1 more source

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