Results 101 to 110 of about 181,370 (308)

Genome-Wide Association of Heroin Dependence in Han Chinese.

PLoS ONE, 2016
Drug addiction is a costly and recurring healthcare problem, necessitating a need to understand risk factors and mechanisms of addiction, and to identify new biomarkers.
Gursharan Kalsi, Jack Euesden, Jonathan R I Coleman, Francesca Ducci, Fazil Aliev, Stephen J Newhouse, Xiehe Liu, Xiaohong Ma, Yingcheng Wang, David A Collier, Philip Asherson, Tao Li, Gerome Breen   +12 more
doaj   +1 more source

Physiological responses of Chinese longsnout catfish to water temperature

, 2011
We evaluated the effect of water temperature on the growth and physiology of the Chinese longsnout catfish (Leiocassis longirostris Gunther). The fish were reared at four temperatures (20, 25, 30, and 35 degrees C) and sampled on days 7, 20, and 30.
Xie Shouqi, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China, Han Dong, hand21cn@ihb.ac.cn, Zhu Xiaoming, Yang Yunxia   +5 more
core  

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Network-assisted analysis of primary Sjogren's syndrome GWAS data in Han Chinese

, 2015
Primary Sjogren's syndrome (pSS) is a complex autoimmune disorder. So far, genetic research in pSS has lagged far behind and the underlying biological mechanism is unclear.
Zhang, Kunlin, Fang, Kechi, Wang, Jing
core   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

The Chinese Civilizing Process: Eliasian Thought as an Effective Analytical Tool for the Chinese Cultural Context

, 2009
This thesis is an effort to apply Elias’s thinking on social development to the Chinese social situation. At first glance his account of the civilizing process would appear incompatible with this context, in that, after state formation with the Qin and ...
Stebbins, Andrew
core  

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Pneumomediastinum and Subcutaneous Emphysema After Tracheotomy Tube Decannulation

Open Respiratory Archives, 2020
Yanxia Geng, Renzheng Diao, Hai Lv, Yan Zhang   +3 more
doaj   +1 more source

Impact of LDLR polymorphisms on lipid levels and atorvastatin’s efficacy in a northern Chinese adult Han cohort with dyslipidemia

Lipids in Health and Disease
Background Dyslipidemia, a significant risk factor for atherosclerotic cardiovascular disease (ASCVD), is influenced by genetic variations, particularly those in the low-density lipoprotein receptor (LDLR) gene.
Hong-Liang Zhao, Yang You, Yan Tian, Luyan Wang, Yongqiang An, Guoqiang Zhang, Chang Shu, Mingxin Yu, Yihua Zhu, Qian Li, Yanwei Zhang, Ningling Sun, Songnian Hu, Gang Liu   +13 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source