Results 81 to 90 of about 181,370 (308)

Genetic variants and haplotypes of the UGT1A9, 1A7 and 1A1 genes in Chinese Han

open access: yesGenetics and Molecular Biology, 2012
In this report, we describe combined polymorphisms of the UGT1A9, UGT1A7 and UGT1A1 genes in 100 unrelated, healthy Chinese Han subjects. The functional regions of these genes were sequenced and comprehensively analyzed for genetic polymorphisms.
Xiaoqing Zhang   +7 more
doaj  

Chinese Association of Greater Toledo newsletter, Spring and Summer, 2014

open access: yes, 2014
A newsletter published by the Chinese Association of Greater Toledo (CAGT). CAGT was founded in 1965 to support the Chinese community in and around Toledo, Ohio and uphold Chinese culture, language, and customs.
Chinese Association of Greater Toledo (Toledo, Ohio)
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Nine horn animal Elicitation from Chinese

open access: yes, 2020
Han Zhengkang translates with Wu Decai a story about a magic animal with nine horns. He reads from the file "Nine horn animal (九支角角的故事)" (included in the folder with the same name), first page.
Chirkova, Katia, Han Zhengkang
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Evaluation of CYP2C19 Genetic Variant and Its Lack of Association with Valproic Acid Plasma Concentrations Among Zhuang and Han Schizophrenia Patients in Guangxi

open access: yesPharmacogenomics and Personalized Medicine
Jun Mei Teng,1 Shuiqing Qin,2 Danyu Lu,1 Yefa Gu,3 Shi Jie Tang,3 Qiong Yan,1 Jiawei Yao,1 Chao Zhang1 1Laboratory Department, The Fifth People’s Hospital of Nanning, Nanning, Guangxi Zhuang Autonomous Region, People’s Republic of China; 2Department of ...
Teng JM   +7 more
doaj  

Subcultural Differences in Processing Social and Non-social Positive Emotions Between Han and Uygur Chinese: An ERP Study

open access: yesFrontiers in Psychology, 2019
While previous studies have shown that East-West cultural differences exist in processing different emotional stimuli, potential subcultural differences within a large cultural group are not well understood.
Xinmei Deng   +4 more
doaj   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Between realist and allegorical discourse: a comparative study of Han Shaogongs fiction. [PDF]

open access: yes, 1990
by Ling Tun Ngai.Thesis (M.Phil.)--Chinese University of Hong Kong, 1990.Bibliography: leaves [129]-139.Acknowledgements --- p.iFormat Details --- p.iiIntroduction --- p.1Chapter 1. --- Realism in the Chinese Conte --- p.xtChapter 2.

core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

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