RHC genotyping in Chinese Han population [PDF]
BMC GenomicsBackground The Rh blood group system is characterized by its complexity and polymorphism, encompassing 56 different antigens. Accurately predicting the presence of the C antigen using genotyping methods has been challenging.
Lin-Nan Shao +5 more
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Genomic insight into the population history of Central Han Chinese
Annals of Human Biology, 2021 Background In recent decades, considerable attention has been paid to exploring the population genetic characteristics of Han Chinese, mainly documenting a north-south genetic substructure.
Guanglin He, Jin Sun, Hui-Zhen Cheng
exaly +4 more sources
Genetic Variation of 25 Y-Chromosomal and 15 Autosomal STR Loci in the Han Chinese Population of Liaoning Province, Northeast China [PDF]
PLoS ONE, 2016 In the present study, we investigated the genetic characteristics of 25 Y-chromosomal and 15 autosomal short tandem repeat (STR) loci in 305 unrelated Han Chinese male individuals from Liaoning Province using AmpFISTR® Yfiler® Plus and IdentifilerTM PCR ...
Jun Yao, Bao-Jie Wang
exaly +2 more sources
Ancestry Informative Marker Set for Han Chinese Population [PDF]
G3: Genes, Genomes, Genetics, 2012 Abstract The population of Han Chinese is ∼1.226 billion people. Genetic heterogeneity between northern Han Chinese (N-Han) and southern Han Chinese (S-Han) has been demonstrated by recent genome-wide studies. As an initial step toward health disparities and personalized medicine in Chinese population, this study developed a set of ...
Hui-Qi Qu +2 more
exaly +3 more sources
Genetic susceptibility to high myopia in Han Chinese population
Open Life Sciences, 2022 High myopia is a common ocular genetic disease in the world. The study sought to investigate the effect of the Insulin-like growth factor-1 (IGF-1) and Matrix metalloproteinase-9 (MMP-9) genes polymorphisms on high myopia in a Han population of China ...
Li Yufei +9 more
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A potential marker DYF371 for differentiating han population from non-han population in Chinese
Journal of Forensic Science and Medicine, 2020 DYF371 locus and single-nucleotide polymorphisms (SNPs) defined as DYF371C or DYF371T were simultaneously examined for 142 Chinese unrelated male individuals, including 90 Han population and 52 minorities.
Hailun Nan, Dejian Lu
doaj +2 more sources
Gene interaction analysis of psoriasis in Chinese Han population
Molecular Genetics & Genomic Medicine, 2022 Background/aims Psoriasis is a chronic immune‐mediated inflammatory skin disease characterized by excessive proliferation of keratinocytes. It has a strong genetic predisposition; gene‐gene interactions are important genetic models for common diseases ...
Qiongqiong Xu +15 more
doaj +3 more sources
B3GNT2, GPR35, PSMG1 Gene Polymorphisms Are Related With Susceptibility and Severity of Ankylosing Spondylitis in Chinese Han Population [PDF]
Molecular Genetics & Genomic MedicineBackground Latest research on ankylosing spondylitis (AS) indicates a link between the B3GNT2, PSMG1 genes and susceptibility to AS among western populations.
Zijian Lian +8 more
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Analysis of MIR155HG gene polymorphisms and ulcerative colitis susceptibility in the Chinese Han Population [PDF]
Non-coding RNA ResearchAberrant expression of miR-155 has been implicated in the pathogenesis of inflammatory bowel disease (IBD), where its dysregulation may contribute to impaired intestinal barrier integrity and sustained inflammation.
Chao Xu +16 more
doaj +2 more sources
ULK1 gene polymorphisms and severe tuberculosis in the Chinese Han population: a case-control study [PDF]
Frontiers in MedicineObjectivesPolymorphisms in the uncoordinated 51-like kinase 1 (ULK1) gene are associated with susceptibility to multiple diseases, including neurodegenerative disorders and specific cancer types.
Juan Zhang, Juan Zhang, Jian-Qing He
doaj +2 more sources