Results 11 to 20 of about 771,775 (343)

Genetic susceptibility to high myopia in Han Chinese population

Open Life Sciences, 2022
High myopia is a common ocular genetic disease in the world. The study sought to investigate the effect of the Insulin-like growth factor-1 (IGF-1) and Matrix metalloproteinase-9 (MMP-9) genes polymorphisms on high myopia in a Han population of China ...
Li Yufei, Zhang Yong, Zhang Ping, Gao Lei, Ma Qingyue, Li Jin, Wang Shengxia, Liu Bing, Wang Xinye, Meng Chao   +9 more
doaj   +3 more sources

Gene interaction analysis of psoriasis in Chinese Han population

Molecular Genetics & Genomic Medicine, 2022
Background/aims Psoriasis is a chronic immune‐mediated inflammatory skin disease characterized by excessive proliferation of keratinocytes. It has a strong genetic predisposition; gene‐gene interactions are important genetic models for common diseases ...
Qiongqiong Xu, Xiaodong Zheng, Yiwen Mao, Weiwei Chen, Shirui Chen, Hui Zhang, Qi Zhen, Bao Li, Liang Yong, Huiyao Ge, Yafen Yu, Ruixue Zhang, Lu Cao, Hui Cheng, Wenjun Wang, Liangdan Sun   +15 more
doaj   +3 more sources

Ancestry Informative Marker Set for Han Chinese Population [PDF]

G3 Genes|Genomes|Genetics, 2012
Abstract The population of Han Chinese is ∼1.226 billion people. Genetic heterogeneity between northern Han Chinese (N-Han) and southern Han Chinese (S-Han) has been demonstrated by recent genome-wide studies. As an initial step toward health disparities and personalized medicine in Chinese population, this study developed a set of ...
Qu, Hui-Qi, Li, Quan, Xu, Shuhua, McCormick, Joseph B., Fisher-Hoch, Susan P., Xiong, Momiao, Qian, Ji, Jin, Li   +7 more
openaire   +4 more sources

Forensic characterization and genetic polymorphisms of 19 X-chromosomal STRs in 1344 Han Chinese individuals and comprehensive population relationship analyses among 20 Chinese groups. [PDF]

PLoS ONE, 2018
X-chromosomal short tandem repeats (X-STRs) may assist resolution of complex forensic kinship cases and complement autosomal and Y-chromosomal STRs in routine forensic practice and population genetics.
Pengyu Chen, Guanglin He, Xing Zou, Mengge Wang, Fuquan Jia, Huiru Bai, Jida Li, Jian Yu, Yanyan Han   +8 more
doaj   +3 more sources

Polymorphism of KIR2DL4 gene among northern Chinese Han population

Zhongguo shuxue zazhi, 2022
Objective To investigate the polymorphism of KIR2DL4 gene in northern Chinese Han population. Methods A total of 327 DNA samples were isolated by magnetic beads from unrelated individuals of northern Chinese Han population.
Zhichao YANG, Hao CHEN, Li NING, Ying LIU, Zhihui DENG   +4 more
doaj   +2 more sources

Wilson Disease in the South Chinese Han Population [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2014
Purpose:To prospectively investigate the incidence and prevalence of Wilson disease (WD) in Chinese Han population in Anhui Province, to analyze the genetic mutations in individuals with WD, and to provide basic epidemiological data regarding WD in this Chinese Han population.Methods:Between November 2008 and June 2010, individuals aged from 7 to 75 ...
Nan, Cheng, Kai, Wang, Wenbin, Hu, Daoyin, Sun, Xun, Wang, Jiyuan, Hu, Renmin, Yang, Yongzhu, Han   +7 more
openaire   +2 more sources

RHC genotyping in Chinese Han population

, 2023
Abstract The Rh blood group is a complex, polymorphic system with 56 antigens. Accurately predicting the presence of the C antigen using genotyping methods has been challenging. This study aimed to evaluate different genotyping methods for C predicting and identifying associated genetic variations in the Chinese Han population.
Lin-Nan Shao, Zi-Wei Zheng, Shi-Hang Zhou, Shu-Ting Zhang, Wen-Qian Song, Yue-Xin Xia, Xiao-Hua Liang   +6 more
openaire   +1 more source

A Genome Wide Association Study Identifies Common Variants Associated with Lipid Levels in the Chinese Population [PDF]

, 2013
Plasma lipid levels are important risk factors for cardiovascular disease and are influenced by genetic and environmental factors. Recent genome wide association studies (GWAS) have identified several lipid-associated loci, but these loci have been ...
Chang, Jiang, Chen, Weihong, Dai, Xiayun, Deng, Qifei, Fang, Weimin, Gao, Yong, Guo, Huan, He, Meian, He, Yunfeng, Hu, Frank B., Huang, Suli, Lang, Mingjian, Li, Dongfeng, Li, Huaixing, Liang, Yuan, Lilly Zheng, S., Lin, Dafeng, Lin, Dongxin, Lin, Xu, Miao, Xiaoping, Min, Xinwen, Mo, Zengnan, Qin, Xue, Sun, Jielin, Tan, Aihua, Tan, Wen, Wang, Feng, Wang, Yiqin, Wang, Youjie, Wei, Sheng, Wu, Chen, Wu, Tangchun, Xu, Jianfeng, Yang, Handong, Yang, Xiaobo, Yu, Dianke, Yuan, Jing, Zhai, Kan, Zhang, Haiying, Zhang, Xiaomin, Zhou, Li, Zhu, Jiang, Zhu, Jingwen   +42 more
core   +9 more sources

Contribution of PNPLA3 gene polymorphisms to hepatocellular carcinoma susceptibility in the Chinese Han population

BMC Medical Genomics, 2022
Objectives The purpose of this study was to investigate the association of PNPLA3 single nucleotide polymorphisms (SNPs) (rs738409 C > G, rs3747207 G > A, rs4823173 G > A, and rs2896019 T > G) with hepatocellular carcinoma (HCC) susceptibility.
Dongwei Gong, Shizong Li, Zhiwei Yu, Kaiqiong Wang, Xin Qiao, Changxiong Wu   +5 more
doaj   +1 more source

Clinical Characteristics of Intraocular Lens Dislocation in Chinese Han Populations [PDF]

Journal of Ophthalmology, 2020
Purpose. To investigate the clinical characteristics of patients with intraocular lens (IOL) dislocation after IOL implantation in Chinese Han populations. Methods. The medical records of patients with IOL dislocation were retrospectively reviewed from January 2007 to December 2017, and a total of 312 patients (male: 231, female: 97) (328 eyes) were ...
Qi Fan, Xiaoyan Han, Xiangjia Zhu, Lei Cai, Xiaodi Qiu, Yi Lu, Jin Yang   +6 more
openaire   +3 more sources