Results 21 to 30 of about 771,775 (343)
BMC Medical Genomics, 2023 Purpose The research aimed to detect the association between single nucleotide polymorphisms (SNPs) in CYP4V2 gene and coronary heart disease (CHD) risk. Methods This case–control study included 487 CHD subjects and 487 healthy individuals.
Kang Huang +9 more
doaj +1 more source
Variants of the low oxygen sensors EGLN1 and HIF-1AN associated with acute mountain sickness. [PDF]
, 2014 Two low oxygen sensors, Egl nine homolog 1 (EGLN1) and hypoxia-inducible factor 1-α inhibitor (HIF-1AN), play pivotal roles in the regulation of HIF-1α, and high altitude adaption may be involved in the pathology of acute mountain sickness (AMS).
Huang, Lan +5 more
core +3 more sources
Environmental Health and Preventive Medicine, 2020 Background We aim to explore the association between self-reported snoring and hypertension among adults aged 30–79 in Chongqing, China. Methods A total of 23,342 individuals aged 30–79 were included at baseline from August 2018 to January 2019, and the ...
Meng Xiao +11 more
doaj +1 more source
Frontiers in Genetics, 2020 Keratoconus (KC) is a complex ocular disease that is affected by both genetic and non-genetic triggers. A recent genome-wide association study (GWAS) identified a genome-wide significant locus for KC in the region of PNPLA2 (rs61876744), as well as a ...
Jing Zhang +11 more
doaj +1 more source
Body weights in Han Chinese populations
Chinese Science Bulletin, 2014 The body weights of 26,954 Han Chinese adults in 67 areas (16,503 in rural areas and 10,451 in urban areas) across China were measured from 2009 to 2013. The results showed that in China, the three areas (north China, northeast China, and Jianghuai Plain) were with the greatest body weight. Northwest Han Chinese populations were heavier.
Yonglan Li +11 more
openaire +1 more source
Association between STAT4 gene polymorphism and type 2 diabetes risk in Chinese Han population
BMC Medical Genomics, 2021 Background Evidence from genetic epidemiology indicates that type 2 diabetes (T2D) has a strong genetic basis. Activated STAT4 has an inflammatory effect, and STAT4 is an important mediator of inflammation in diabetes.
Jiaqi Cui +12 more
doaj +1 more source
Genome-wide association study of serum tumor markers in Southern Chinese Han population
BMC Cancer, 2022 Background Serum indicators AFP, CA50, CA125, CA153, CA19-9, CEA, f-PSA, SCC-Ag have been confirmed as tumor markers (TMs). We conducted a genome-wide association study on 8 tumor markers of our 427 Han population in southern China, in order to identify ...
Xiukuan Li +13 more
doaj +1 more source
BMC Cardiovascular Disorders, 2019 BackgroundNeutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are assumed to be prognostic factors in many diseases such as inflammatory diseases, cardiovascular diseases and cancer.
Lishan Wu +4 more
semanticscholar +1 more source
International Journal of Infectious Diseases, 2015 Objective: Leprosy and tuberculosis (TB) are chronic granulomatous infectious diseases. As well as pathogen and environmental factors, host genetic factors make a substantial contribution to susceptibility to both diseases.
Chuan Wang +7 more
doaj +1 more source
Spectrum of malignancies among the population of adults living with HIV infection in China: A nationwide follow-up study, 2008-2011. [PDF]
, 2019 BackgroundAlthough increasingly studied in high-income countries, there is a paucity of data from the Chinese population on the patterns of cancer among people living with HIV (PLHIV).MethodsWe conducted a nationwide follow-up study using routinely ...
Detels, Roger +7 more
core +2 more sources