Results 51 to 60 of about 12,027 (230)

Depression, risk factors, and coping strategies in the context of social dislocations resulting from the second wave of COVID-19 in Japan

BMC Psychiatry, 2021
Background Social dislocations resulting from coronavirus disease 2019 (COVID-19) pandemic have been prolonged, which has led to general population social suppression.
Yuko Fukase, Kanako Ichikura, Hanako Murase, H. Tagaya   +3 more
semanticscholar   +1 more source

Targeting SPP1‐CD44‐Hedgehog Axis Elicits Therapeutic Effects in Hepatocellular Carcinoma by Suppressing Intratumoral Fibrosis

Cancer Science, EarlyView.
SPP1 was identified as a key driver of intratumoral fibrosis and hepatocellular carcinoma (HCC) progression through transcriptomic, histological, and functional analyses. Mechanistically, SPP1 promotes HSC activation and fibrosis via the SPP1–CD44–GLI1 axis, and pharmacologic inhibition of Hedgehog signaling effectively reduces tumor growth and ...
Atsushi Nara, Shu Shimada, Yoshimitsu Akiyama, Megumi Hatano, Yusuke Chino, Suguru Miyazawa, Hanako Tamura, Daisuke Asano, Yoshiya Ishikawa, Hiroki Ueda, Shuichi Watanabe, Eriko Katsuta, Keiichi Akahoshi, Kenichi Ohashi, Minoru Tanabe, Daisuke Ban, Shinji Tanaka   +16 more
wiley   +1 more source

Counterfactuals, indicative conditionals, and negation under uncertainty: Are there cross-cultural differences? [PDF]

, 2017
In this paper we study selected argument forms involving counterfactuals and indicative conditionals under uncertainty. We selected argument forms to explore whether people with an Eastern cultural background reason differently about conditionals ...
Pfeifer, Niki, Yama, Hiroshi
core   +1 more source

Comparison of pharmacodynamics and pharmacokinetics of ultra‐rapid‐acting insulin aspart and rapid‐acting insulin aspart around continuous moderate intensity exercise in adults with type 1 diabetes: A randomised controlled trial

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims To compare the effects of dose reductions of ultra‐rapid‐acting insulin aspart (URA‐IAsp) and rapid‐acting insulin aspart (IAsp) on blood glucose concentrations during continuous moderate‐intensity exercise in people with type 1 diabetes (T1D).
Jason P. Pitt, Alexander Müller, Chloe Nicholas, Olivia M. McCarthy, Othmar Moser, Stephen C. Bain, Harald Sourij, Richard M. Bracken   +7 more
wiley   +1 more source

Wh-questions in Japanese: scrambling, reconstruction, and wh-movement [PDF]

, 2002
In this article, I discuss some important properties of wh-questions and wh-scrambling in Japanese. The questions I will address are (i) which instances of (wh-) scrambling involve reconstruction and (ii) how the undoing effects of scrambling can be ...
Sabel, Joachim
core  

Machine Learning Approach Enables Highly Accurate Identification of At‐Risk Metabolic Dysfunction‐Associated Steatohepatitis

Hepatology Research, EarlyView.
ABSTRACT Aim At‐risk metabolic dysfunction‐associated steatohepatitis (MASH), characterized by significant activity and fibrosis, increases the risk of liver complications. Liver stiffness measurement (LSM), commonly used to detect significant fibrosis, has limitations in terms of accessibility and performance in certain populations.
Masaya Sato, Takuma Nakatsuka, Tatsuya Minami, Yotaro Kudo, Rie Irie, Hanako Tsujikawa, Takumi Kawaguchi, Hirokazu Takahashi, Yuichiro Eguchi, Eisuke Murakami, Kazuaki Chayama, Takeshi Okanoue, Michiie Sakamoto, Mitsuhiro Fujishiro, Kazuhiko Koike, Ryosuke Tateishi   +15 more
wiley   +1 more source

Gaze as a Window to the Process of Novel Adjective Mapping

Languages, 2019
This study evaluated two explanations for how learning of novel adjectives is facilitated when all the objects are from the same category (e.g., exemplar and testing objects are all CUPS) and the object category is a known to the children.
Hanako Yoshida, Aakash Patel, Joseph Burling   +2 more
doaj   +1 more source

Feasibility of Novel Slim Peroral Cholangiopancreatoscopy for the Diagnosis of Pancreatobiliary Disease

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives To evaluate the clinical outcomes of peroral cholangiopancreatoscopy (POCPS) using the 9‐Fr eyeMAX for the diagnosis of pancreatobiliary diseases. Methods This retrospective study enrolled 43 patients who underwent POCPS using the 9‐Fr eyeMAX for diagnostic procedures at two tertiary referral centers between May 2023 and November ...
Haruo Miwa, Kazuya Sugimori, Kuniyasu Irie, Yoshihiro Goda, Kozue Shibasaki, Yugo Ishino, Shotaro Tsunoda, Kazuki Endo, Ritsuko Oishi, Yuichi Suzuki, Hiromi Tsuchiya, Akihiro Funaoka, Hideyuki Anan, Yoshimasa Suzuki, Takashi Kaneko, Manabu Morimoto, Kazushi Numata, Shin Maeda   +17 more
wiley   +1 more source

Japanese wa, mo, ga, wo, na, no [PDF]

, 2010
Lone Takeuchi’s stimulating book (1999) has given me an opportunity to reconsider my (unpublished) semiotactic analysis of Japanese particles [...]
Kortlandt, Frederik H. H.
core  

Integrated extracellular microRNA profiling for ovarian cancer screening

Nature Communications, 2018
A major obstacle to improving prognoses in ovarian cancer is the lack of effective screening methods for early detection. Circulating microRNAs (miRNAs) have been recognized as promising biomarkers that could lead to clinical applications.
A. Yokoi, Juntaro Matsuzaki, Yusuke Yamamoto, Y. Yoneoka, Kenta Takahashi, H. Shimizu, T. Uehara, M. Ishikawa, S. Ikeda, Takumi Sonoda, J. Kawauchi, S. Takizawa, Yoshiaki Aoki, S. Niida, H. Sakamoto, Ken Kato, Tomoyasu Kato, T. Ochiya   +17 more
semanticscholar   +1 more source