Results 31 to 40 of about 81,923 (299)

Pazopanib induced hand-foot syndrome

open access: yesOxford Medical Case Reports, 2015
A 55-year-old male was diagnosed as a case of metastatic renal cell carcinoma (clear cell histology) and started on tyrosine kinase inhibitor (TKI) pazopanib. He reported back to us 2 weeks later with painful, erythematous and desquamating lesions of the hands and soles. On examination, erythematous and desquamating lesion involving dorsum of hands and
Sundriyal, Deepak, Kumar, Naveen
openaire   +2 more sources

Paclitaxel-induced periarticular thenar eminence erythema with onycholysis: A case report

open access: yesSAGE Open Medical Case Reports, 2023
Paclitaxel is a drug frequently used in the treatment of gynecological cancers. Its cutaneous side effects are fairly well documented. A subtype of hand-foot syndrome, periarticular erythema of the thenar eminences with onycholysis, is rarer.
François Charron-Ligez   +2 more
doaj   +1 more source

New Clinical Application of Chaihu Decoction

open access: yesChinese Medicine and Natural Products, 2022
The classified prescriptions from Chaihu decoction have been widely used in ancient and modern times. In spite of many previous research studies, the extensiveness and diversity of their applications have not been systematically studied.
Bo Huang, Yingfeng Liu, Yajing Lyu
doaj   +1 more source

The Diabetic Foot Syndrome Today A Pandemic Uprise

open access: yes, 2017
Diabetes mellitus is growing at epidemic proportions worldwide; currently 415 million adults are estimated to have diabetes and by 2040, this number is estimated to increase to 642 million.
Lund University., Apelqvist, Jan,
core   +1 more source

Palmar-plantar erythrodysesthesia: An uncommon adverse effect of everolimus

open access: yesIndian Journal of Medical and Paediatric Oncology, 2016
Mammalian target of rapamycin inhibitor everolimus is a novel agent used in endocrine therapy resistant hormone receptor positive metastatic breast cancer.
Shalabh Arora   +3 more
doaj   +1 more source

The development of hand preference in children: The effect of task demands and links with manual dexterity

open access: yes, 2009
Lateralisation of hand preference and manual dexterity are known to develop over childhood, while in adulthood strength of hand preference has been shown to interact with extrinsic task demands.
Hill, Elisabeth L., Khanem, Fateha
core   +1 more source

Predictors of Hand-Foot Syndrome and Pyridoxine for Prevention of Capecitabine–Induced Hand-Foot Syndrome

open access: yesJAMA Oncology, 2017
Hand-foot syndrome (HFS) is a common adverse effect of capecitabine treatment.To compare the incidence and time to onset of grade 2 or greater HFS in patients receiving pyridoxine vs placebo and to identify biomarkers predictive of HFS.This single-center, randomized double-blind, placebo-controlled phase 3 trial conducted at National Cancer Centre ...
Yoon-Sim, Yap   +17 more
openaire   +3 more sources

Loss of the BMP antagonist, SMOC-1, causes Ophthalmo-Acromelic (Waardenburg Anophthalmia) syndrome in humans and mice [PDF]

open access: yes, 2011
Ophthalmo-acromelic syndrome (OAS), also known as Waardenburg Anophthalmia syndrome, is defined by the combination of eye malformations, most commonly bilateral anophthalmia, with post-axial oligosyndactyly.
Jackson, Ian J.   +167 more
core   +1 more source

Risk Factors for Failure After Surgery in Patients With Diabetic Foot Syndrome [PDF]

open access: yes, 2023
Background: In the present study, we aimed to identify risk factors for failure (defined as reoperation within 60 days) after debridement or amputation at the lower extremity in patients with diabetic foot syndrome and to develop a model using the ...
David Vonwyl   +11 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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