Results 41 to 50 of about 14,434,144 (306)

G protein‐coupled receptors: walking hand‐in‐hand, talking hand‐in‐hand? [PDF]

open access: yesBritish Journal of Pharmacology, 2011
Most cells express a panel of different G protein‐coupled receptors (GPCRs) allowing them to respond to at least a corresponding variety of extracellular ligands. In order to come to an integrative well‐balanced functional response these ligand–receptor pairs can often cross‐regulate each other.
Vischer, H.F.   +3 more
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Long-term patient-reported outcomes for open surgery of the triangular fibrocartilage complex

open access: yesBone & Joint Open, 2021
Aims: Studies on long-term patient-reported outcomes after open surgery for triangular fibrocartilage complex (TFCC) are scarce. Surgeons and patients would benefit from self-reported outcome data on pain, function, complications, and satisfaction after ...
Reinier Feitz   +7 more
doaj   +1 more source

Generation of optical quality structured surfaces on borosilicate glass using 515nm picosecond laser pulses and a liquid-crystal-based spatial light modulator [PDF]

open access: yes, 2012
Liquid-crystal-based spatial light modulators (LC-SLMs) are electrically programmable devices which allow us to modulate the phase and amplitude of the linear-polarised light.
Hand, Duncan Paul   +1 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Temperature compensated digital inertial sensor [PDF]

open access: yes, 1974
A circuit which maintains the inertial element of a gyroscope or accelerometer at a constant position by delivering pulses to a rebalancing motor is discussed.
Hand, P. J.
core   +1 more source

Real time hand gesture recognition including hand segmentation and tracking [PDF]

open access: yes, 2006
In this paper we present a system that performs automatic gesture recognition. The system consists of two main components: (i) A unified technique for segmentation and tracking of face and hands using a skin detection algorithm along with handling ...
A. Shamaie   +4 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Temperature compensation of digital inertial sensors [PDF]

open access: yes, 1974
Heaters for thermal stabilization are unnecessary when analog dc voltage provided by gyroscope temperature sensor is used to change outputs to compensate for temperature variations.
Hand, P. J.
core   +1 more source

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