Results 51 to 60 of about 14,434,144 (306)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Acta Orthopaedica, 2020 Background and purpose — Elderly patients may benefit from a dislocation low-risk dual-mobility (DM) articulation in total hip arthroplasty, but the best cup fixation method is unknown.
Steffan Tabori-Jensen +3 more
doaj +1 more source
Mediators of Inflammation, 2022 Osteoarthritis (OA), a chronic degenerative joint disease, always occurred in the aging population. There is evidence suggests that chondrocytes’ survival, inflammation, and apoptosis play critical roles in OA pathogenesis.
Yiping Mu, Lining Wang, Ling Fu, Qi Li
doaj +1 more source
Simulation, no problem, of course we offer this service! (observations on firms who have worked to make this true) [PDF]
, 2002 The paper focuses on the practical experiences of a number of professional firms striving to use simulation to deliver information of value to their clients.
Hand, Jon, McElroy, Lori
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biotechnology & Biotechnological Equipment, 2020 The aim of the present study was to determine the expression of MCP-1 in injured cartilage tissues, peripheral blood and synovial fluid from patients with cartilage injury of elbow joint of upper limbs, and try to understand its relationship with ...
Feng Zhu, Jie Yin, Junjie Li, Jianbo Xue
doaj +1 more source
CFD assessments within strongly transient domains [PDF]
, 2007 Assessments based on CFD snapshots of stable conditions within strongly transient domains do not address many aspects of performance associated with occupant interventions, control actions or changing climate. Such domains (e.g.
Hand, J., Samuel, A.A.A.
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Ghost hand: My hand is not mine [PDF]
, 2009 Synchronous visuo-tactile stimulation of the type in the rubber hand illusion (RHI)^1-3^ and in out of body experience (OBE)^4,5^ can induce the brain to incorporate external objects or images into a part or whole of body image. Whether in the context of
Shinpei Tatsumi +3 more
core +1 more source