Results 71 to 80 of about 5,111,327 (413)

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Profile of hand injuries in a specialist hospital in a developing country [PDF]

, 2018
Background:Hand injuries are common in this environment.They are rarely life threatening but can cause serious handicap.There is paucity of studies addressing the pattern and management of hand injuries in this locality.Patients and Methods: This is a ...
Mba, U.C., Nnabuko, R.E.E., Okwor, B.C.
core   +2 more sources

Epidemiology of isolated hand injuries in the United Arab Emirates

World Journal of Orthopaedics, 2016
AIM To provide suggestions for hand injury prevention by study the demography and risk factors of casualties suffering from isolated hand injuries. METHODS All trauma patients with isolated hand injuries who were admitted to Al Ain Hospital for more than
M. Grivna, H. Eid, F. Abu-Zidan
semanticscholar   +1 more source

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

FEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel, Qian He, Yixin Kang, Dianbao Zhang, Min Gao, Minglin Wang, Kexin Fan, Jingwen Xiong, Shaobo Wu, Botao Fa, Zhengtao Xiao, Yingfang Niu, Jun Yao, Yilei Zhang   +13 more
wiley   +1 more source

Treatment notes: Treatment of hand injuries

South African Journal of Physiotherapy, 1960
No abstract available.
Joan E. Youthed, Keith Nicol
doaj   +1 more source

Grinder Injury of the Hand: A Rare but Devastating Occupational Hazard

The Surgery Journal, 2021
Food handlers and workers are exposed to several occupational hazards not frequented by the general population. Grinder injuries of the hand present a devastating consequence of industrial food processing that is infrequently described.
Tushar Patial, Rajinder K. Mittal, Ramneesh Garg, Sheerin Shah, Amandeep Kaur   +4 more
doaj   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

Upper extremity high-pressure injection injuries with paint thinner: Case reports with review of the literature

Turkish Journal of Plastic Surgery, 2021
Introduction: High-pressure injection injuries are rare traumas of upper extremity which can result in high morbidity incompatible with presentation.
Bugra Ipek, Ugurcan Sener, Feridun Elmas, Ergin Seven, Aysegul Uslu, Sebat Karamursel   +5 more
doaj   +1 more source

Multi-Contact Force-Sensing Guitar for Training and Therapy [PDF]

arXiv, 2023
Hand injuries from repetitive high-strain and physical overload can hamper or even end a musician's career. To help musicians develop safer playing habits, we developed a multiplecontact force-sensing array that can substitute as a guitar fretboard.
arxiv  

Improving organ dose sparing in left‐sided breast cancer with yaw‐limited volumetric modulated arc therapy: A dosimetric comparison to conventional and intensity modulated radiation therapy approaches

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background To assess the dose‐sparing capabilities of a yaw‐limited volumetric modulated arc therapy (YL_VMAT) beam setup for adjacent organs at risk (OAR) in comparison with 3D‐conventional radiation therapy (3D‐CRT), intensity‐modulated radiation therapy (IMRT) and conventional VMAT for radiation therapy in left‐sided breast cancer patients.
Gerhard Pollul, Sascha Grossmann, Heiko Karle, Tilman Bostel, Heinz Schmidberger   +4 more
wiley   +1 more source