Results 41 to 50 of about 730,433 (314)

Measuring hand grip strength in rheumatoid arthritis

Rheumatology International, 2018
Rheumatoid arthritis (RA) is a systemic inflammatory disease with a particular predilection for causing pain, deformity and functional limitation affecting the hands. Measures of the severity of RA, such as the disease activity score with 28 joint count may not fully reflect the regional impact of RA on the hands.
Susie C. Higgins, Jo Adams, Rodney Hughes   +2 more
openaire   +5 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Correlation between handgrip strength and carrying angle in young women with different body mass indices – A cross-sectional observation study

Revista Pesquisa em Fisioterapia
| INTRODUCTION: Hand grip strength is an indicator to predict the health status of individuals in clinical practice. Age, gender, anthropometric characteristics, and health status influence grip strength performance of the hand through their influence on
Kshama Susheel Shetty, Rashmi Ravi Kotennavar, Hariharasudhan Ravichandran   +2 more
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Evaluation of quality of life, functionality and disability in patients with systemic sclerosis in a University Hospital

ABCS Health Sciences, 2020
Introduction: Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by progressive fibrosis of the skin and internal organs that promotes high morbidity and mortality.
Amanda Maria da Silva, Letticia Cristina Santos Cardozo Roque, Rafaela Silva Guimarães Gonçalves, Angela Luzia Branco Pinto Duarte, Angélica da Silva Tenório, Andréa Tavares Dantas   +5 more
doaj   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Secular trends in grip strength among Korean adults according to socioeconomic factors: the 2014-2022 Korea National Health and Nutrition Examination Survey [PDF]

Epidemiology and Health
OBJECTIVES Muscle strength is a key indicator of overall health, and its decline has been linked to increased morbidity and mortality. Socioeconomic factors may contribute to disparities in this decline.
Harim Choe, Hoyong Sung, Yeon Soo Kim
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Prediction of hand strength by hand injury severity scoring system in hand injured patients

Disability and Rehabilitation, 2011
Hand strength is a key component in human hand function, especially to those with strength-required jobs. To evaluate post-injury hand strength, this study was conducted to assess the predictability of hand injury severity scoring (HISS) system to hand strength after a period of recovery.In this retrospective study, 80 traumatic hand-injured subjects ...
Delmar C Y, Lin, Jer-Hao, Chang, Shyh-Jou, Shieh, Feruth H J, Tsai, Yungling Leo, Lee   +4 more
openaire   +2 more sources

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source