Results 51 to 60 of about 10,315,212 (291)

Increased Extracellular-to-Total Body Water Ratio in Community-Dwelling Individuals in their 20s to 90s is Associated with Decreased Grip Strength and Gait Speed [PDF]

Annals of Geriatric Medicine and Research
Background In 2019, the European Working Group of Sarcopenia in Older People indicated the importance of assessing muscle mass and quality in diagnosing sarcopenia.
Akemi Hioka, Naoki Akazawa, Naomi Okawa, Shinji Nagahiro   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Nutrition and handgrip strength of older adults in rural Malawi. [PDF]

, 2001
OBJECTIVE: To examine the relationship between the nutritional status and handgrip strength of older people in rural Malawi. DESIGN: Cross-sectional study. SETTING: : Lilongwe rural, Malawi, situated approximately 35-50 km from the city. SUBJECTS: Ninety
Ismail, SJ, Chilima, DM
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Association of Body Shape Index (ABSI) with Hand Grip Strength

International Journal of Environmental Research and Public Health, 2020
Hand grip is a leading measure of muscle strength and general health, yet its association with body shape is not well characterized. Here, we examine correlations between grip strength, a body shape index (ABSI), and body mass index (BMI) in the 2011 ...
N. Krakauer, J. Krakauer
semanticscholar   +1 more source

Strengthening and stretching for rheumatoid arthritis of the hand (SARAH): design of a randomised controlled trial of a hand and upper limb exercise intervention - ISRCTN89936343 [PDF]

, 2012
Background: Rheumatoid Arthritis (RA) commonly affects the hands and wrists with inflammation, deformity, pain, weakness and restricted mobility leading to reduced function.
Toye, Francine, Lamb, S. E. (Sallie E.), Williamson Esther M, Adams, Jo, Nichols, Vivien P., Heine Peter, McConkey Christopher, Mark A Williams, Nicols, Vivien, Underwood, Martin, Bridle, Christopher, Bridle, C, Lord, J, Bridle, Chris, Esther M Williamson, Joanne Lord, Heine, Peter, Williamson, Esther, Christopher McConkey, Williams, MA, Lamb, Sarah, null null, Heine, Peter J., Dosanjh Sukhdeep, Adams Jo, Francine Toye, Lamb Sarah E, Williams, Mark A., Sukhdeep Dosanjh, Lamb, SE, Chris Bridle, McConkey, Christopher C., Toye, F, Nichols Vivien, Heine, P, Underwood Martin R, Toye Francine, HASH(0x55a6805dc180), Bridle Chris, Williamson, EM, Martin R Underwood, Williams Mark A, Dosanjh, S, Underwood, MR, Jo Adams, Adams, J, Lord, J., McConkey, Christopher, Vivien Nichols, Sarah Trial Team, The, Lord, Joanne, Williams, Mark, Lord Joanne, Dosanjh, Sukhdeep, Nichols, V, Sarah E Lamb, McConkey, C, Peter Heine, Williamson, Esther M.   +58 more
core   +2 more sources

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Inverse Correlation Between Grip Strength and Serum Phosphorus: A Retrospective Observational Study in Japanese Elderly with Poorly Controlled Type 2 Diabetes

Geriatrics, 2020
The aim of this study was to investigate factors associated with sarcopenia among elderly patients with poorly controlled diabetes mellitus (DM). We retrospectively analyzed 41 patients with type 2 DM, aged ≥65 years who required diabetes education ...
Sho Tanaka, Masahiro Takubo, Genta Kohno, Masaru Kushimoto, Jin Ikeda, Katsuhiko Ogawa, Yutaka Suzuki, Masanori Abe, Hisamitsu Ishihara, Midori Fujishiro   +9 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Association between handgrip strength and physical activity in hypertensive elderly individuals

Revista Brasileira de Geriatria e Gerontologia
Introduction : Handgrip is an excellent indicator of functionality, nutritional status and mortality among the elderly. Objective: To compare the handgrip strength of hypertensive elderly individuals classified by different levels and types of physical ...
Rafaela Ávila Mattioli, Adriana Schüler Cavalli, José Antônio Bicca Ribeiro, Marcelo Cozzensa da Silva   +3 more
doaj   +1 more source