Results 51 to 60 of about 753,167 (262)

Measuring hand grip strength in rheumatoid arthritis [PDF]

Rheumatology International, 2018
Rheumatoid arthritis (RA) is a systemic inflammatory disease with a particular predilection for causing pain, deformity and functional limitation affecting the hands. Measures of the severity of RA, such as the disease activity score with 28 joint count may not fully reflect the regional impact of RA on the hands.
Susie C. Higgins, Jo Adams, Rodney Hughes   +2 more
openaire   +4 more sources

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Association Between Sodium Density and Grip Strength Among Older Korean Adults: A Nationwide Cross-Sectional Study

Clinical Interventions in Aging, 2019
Hye-Mi Noh,1 Yong Soon Park,2 Hae-Jeung Lee,3 Yong Kyun Roh,4 Hong Ji Song1 1Department of Family Medicine, Hallym University Sacred Heart Hospital, Anyang, Gyeonggi-Do, Republic of Korea; 2Department of Family Medicine, Chuncheon Sacred Heart Hospital ...
Noh HM, Park YS, Lee HJ, Roh YK, Song HJ
doaj  

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Respiratory Function And Muscular Capacity In Old Adults: The Aga@4Life Project [PDF]

Geriatrics, Gerontology and Aging
INTRODUCTION: Age-related muscle changes, translated into a decrease both in muscle imass and functionality, are determinants of a decrease in strength and resistance to exercise in older adults.
Daniel Alexandre Dias Pedroso, Telmo Pereira, Jorge Conde   +2 more
doaj   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Power-Assisted Scissors Reduce Adductor Pollicis Muscle Fatigue: A Comparative Study in Female College Students

Applied Sciences
Hand fatigue commonly occurs in repetitive tasks, such as cutting with scissors, leading to discomfort, reduced productivity, and musculoskeletal disorders.
Kohei Koizumi, Kumiko Sasao, Yoshihiro Senju, Toyohiro Hamaguchi   +3 more
doaj   +1 more source

Evaluation of quality of life, functionality and disability in patients with systemic sclerosis in a University Hospital

ABCS Health Sciences, 2020
Introduction: Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by progressive fibrosis of the skin and internal organs that promotes high morbidity and mortality.
Amanda Maria da Silva, Letticia Cristina Santos Cardozo Roque, Rafaela Silva Guimarães Gonçalves, Angela Luzia Branco Pinto Duarte, Angélica da Silva Tenório, Andréa Tavares Dantas   +5 more
doaj   +1 more source

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source