Results 41 to 50 of about 753,167 (262)

The relationship between smartphone usage duration (using smartphone’s ability to monitor screen time) with hand-grip and pinch-grip strength among young people: an observational study

BMC Musculoskeletal Disorders, 2021
Background The use of smartphones has become widely popular, especially among young people, for multiple purposes other than communication, including gaming and internet browsing.
Ahmad Osailan
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

The midterm results of proximal row carpectomy in the treatment of degenerative wrist joint derangements

Acta Orthopaedica et Traumatologica Turcica, 2020
Objectives: We evaluated the mid-term results of proximal row carpectomy (PRC) in patients who underwent treatment for wrist joint derangements.\nMethods: Nine patients (4 men, 5 women; mean age 38 years; range 23 to 66 years) underwent PRC to relive ...
Hakan Gundes, Hakan Kurt, Levent Buluc, Hatice Erguner   +3 more
doaj  

Secular trends in grip strength among Korean adults according to socioeconomic factors: the 2014-2022 Korea National Health and Nutrition Examination Survey [PDF]

Epidemiology and Health
OBJECTIVES Muscle strength is a key indicator of overall health, and its decline has been linked to increased morbidity and mortality. Socioeconomic factors may contribute to disparities in this decline.
Harim Choe, Hoyong Sung, Yeon Soo Kim
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Metabolic Dysfunction-Associated Steatotic Liver Disease and Low Handgrip Strength Are Associated with a Higher Risk of Cardiovascular Disease

Journal of Obesity & Metabolic Syndrome
Background : We aimed to investigate the influence of metabolic dysfunction-associated steatotic liver disease (MASLD) and handgrip strength (HGS) on the risk of atherosclerotic cardiovascular disease (ASCVD) in the general population.
Eugene Han, Yong-ho Lee, Sang Hoon Ahn, Hye Won Lee, Mi Na Kim, Jae Seung Lee, Byung-Wan Lee, Eun Seok Kang, Bong-Soo Cha, Seung Up Kim   +9 more
doaj   +1 more source

A Cross-sectional Study on Grip Ability Test and its Relation with “Hy” Band: Surrogate Marker for Amyloidosis in Patients with Rheumatoid Arthritis [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Rheumatoid Arthritis (RA) is a chronic inflammatory disease of autoimmune origin. The disease has specific predilection for small joints of the body especially joints of the hand.
KR Senthil Kumari, GJ Swetha Varsha
doaj   +1 more source