Results 91 to 100 of about 119,246 (323)

Cause of Chirality Consensus

, 2009
Biological macromolecules, proteins and nucleic acids are composed exclusively of chirally pure monomers. The chirality consensus appears vital for life and it has even been considered as a prerequisite of life.
Annila, Arto, Jaakkola, Salla, Sharma, Vivek   +2 more
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Exome-wide analysis implicates rare protein-altering variants in human handedness

Nature Communications
Handedness is a manifestation of brain hemispheric specialization. Left-handedness occurs at increased rates in neurodevelopmental disorders. Genome-wide association studies have identified common genetic effects on handedness or brain asymmetry, which ...
Dick Schijven, Sourena Soheili-Nezhad, Simon E. Fisher, Clyde Francks   +3 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

The relationship between handedness and academic achievement in high school students of Sanandaj City, Iran

Chronic Diseases Journal, 2019
BACKGROUND: Academic achievement is considered as one of the main results of the educational system and focusing on factors affecting it is of great importance. The present study was performed with the aim to determine the relationship between handedness
Boshra Vahabi
doaj   +1 more source

Atomic-level handedness determination of chiral crystals using aberration-corrected scanning transmission electron microscopy

Nature Communications, 2020
Handedness or chirality determination of crystals has always been challenging for chemists, biologists and materials scientists. Here, the authors report a method for handedness determination by atomic-resolution imaging using Cs-corrected scanning ...
Zhuoya Dong, Yanhang Ma
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Handedness in autism spectrum disorders and intellectually disabled children and adolescents - Contrasting caregivers’ reports with assessments of hand preference

Heliyon
Background: A higher rate of atypical handedness prevalence (non-right-handedness or left-, mixed-hand dominance) has been recurrently reported in individuals diagnosed with autism spectrum disorder (ASD) compared to individuals with other types of ...
Sayyed Ali Samadi
doaj   +1 more source

Degree of handedness, but not direction, is a systematic predictor of cognitive performance

Frontiers in Psychology, 2013
A growing body of evidence is reviewed showing that degree of handedness (consistent versus inconsistent) is a more powerful and appropriate way to classify handedness than the traditional one based on direction (right versus left).
Eric ePrichard, Ruth E Propper, Stephen D Christman   +2 more
doaj   +1 more source

How to generate families of spinors

, 2003
Using a technique \cite{holgernorma2002} to construct a basis for spinors and ``families'' of spinors in terms of Clifford algebra objects, we define other Clifford algebra objects, which transform the state of one ''family'' of spinors into the state of
Gornik, H. B. Nielsen, Kähler, Kogut, Mankoč Borštnik, Mankoč Borštnik, Mankoč Borštnik, Mankoč Borštnik, Mankoč Borštnik, Mankoč Borštnik, Mankoč Borštnik, N. Mankoč Borštnik, Nielsen   +12 more
core   +1 more source