Results 31 to 40 of about 24,468 (261)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Handling Quality of Woven Fabrics
目的 織物のハンドリングをあらわす特性として, 硬さ, 厚さを選び, これらが人の感覚にどのように感ずるかを調べ合せて物理的特性との関連性を考察し, 織物のハンドリングを評価するための基礎資料をうる.成果濃度のわずかに異なる薄のり液でのり付した綿ブロードについて官能検査によって硬さ, 厚さについて実験した結果を解析してつぎの結果をえた.(1) 硬さのようなわかりやすい特性については判断は比較的よく一致する.(2) 官能による判定は他の特性に大きく影響されるものがある.本実験では厚さが硬さによって左右される結果となっているように, ハンドリングの評価には判定を誤まる要素が多くあると考えられる.(3) 本実験では硬さはハートループおよびカンチレバと比較的一致しているが ...
H. Nakazato, I. Kageyama
openaire +3 more sources
Developing Alsim AL250 based eVTOL flight simulator
A novel eVTOL aircraft simulator was developed for research and teaching purposes. The simulator integrated MATLAB/Simulink flight dynamics model with Alsim AL250 FNPT II flight simulator.
Vilius Portapas
doaj +1 more source
Non-Linear Dynamic Inversion Control Design for Rotorcraft
Flight control design for rotorcraft is challenging due to high-order dynamics, cross-coupling effects, and inherent instability of the flight dynamics.
Joseph F. Horn
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Modern fighter aircraft have been designed to have high maneuverability in order to preoccupy strategic superiority in short-range air-to-air combat between fighter aircraft in warfare.
Chong-Sup Kim +2 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source

