Results 41 to 50 of about 24,468 (261)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Study of The Flying and Handling Qualities of a Glider-Type Aircraft for Instruction Purposes
Ciencia y Poder Aéreo, 2019 The goal of this paper is to conduct a study on the flying and usability attributes of a glider-type aircraft used for instruction. For the development of this project, we propose a dynamic model where we introduce small disturbances to calculate the ...
Yeinson Alfonso Castellanos Sanabria +1 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Aerospace, 2020 The Blended Wing Body (BWB) configuration is considered to have the potential of providing significant advantages when compared to conventional aircraft designs.
Clayton Humphreys-Jennings +2 more
doaj +1 more source
Prediction of pilot induced oscillations [PDF]
INCAS Bulletin, 2011 An important problem in the design of flight-control systems for aircraft under pilotedcontrol is the determination of handling qualities and pilot-induced oscillations (PIO) tendencieswhen significant nonlinearities exist in the vehicle description. The
Valentin PANĂ
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Building Credible VTOL Flight Models for Handling Quality Certification by Simulation
AerospaceCertifying novel VTOL aircraft handling qualities (HQs) may be challenging, relying on costly and high-risk flight testing. This paper presents a methodology to establish the credibility of flight simulation models for certification by simulation, aiming
Lorenzo Favaro +2 more
doaj +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Preparation and Characterization of Al/HTPB Composite for High Energetic Materials
Nanomaterials, 2020 Nanosized Al (nAl) powders offer increased reactivity than the conventional micron-sized counterpart, thanks to their reduced size and increased specific surface area.
Alexander Vorozhtsov +5 more
doaj +1 more source