Results 61 to 70 of about 364,270 (312)
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Flight evaluation of advanced control systems and displays on a general aviation airplane [PDF]
A flight-test program was conducted to determine the effect of advanced flight control systems and displays on the handling qualities of a light twin-engined airplane.
Barber, M. R. +3 more
core +1 more source
Validation and Verification of Aircraft Control Software for Control Improvement [PDF]
Validation and Verification are important processes used to ensure software safety and reliability. The Cooper-Harper Aircraft Handling Qualities Rating is one of the techniques developed and used by NASA researchers to verify and validate control ...
Pham, Thien-Anh
core +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Handling Quality of Woven Fabrics
目的 織物のハンドリングをあらわす特性として, 硬さ, 厚さを選び, これらが人の感覚にどのように感ずるかを調べ合せて物理的特性との関連性を考察し, 織物のハンドリングを評価するための基礎資料をうる.成果濃度のわずかに異なる薄のり液でのり付した綿ブロードについて官能検査によって硬さ, 厚さについて実験した結果を解析してつぎの結果をえた.(1) 硬さのようなわかりやすい特性については判断は比較的よく一致する.(2) 官能による判定は他の特性に大きく影響されるものがある.本実験では厚さが硬さによって左右される結果となっているように, ハンドリングの評価には判定を誤まる要素が多くあると考えられる.(3) 本実験では硬さはハートループおよびカンチレバと比較的一致しているが ...
H. Nakazato, I. Kageyama
openaire +2 more sources
Rotorcraft handling-qualities design criteria development [PDF]
Joint NASA/Army efforts at the Ames Research Center to develop rotorcraft handling-qualities design criteria began in earnest in 1975. Notable results were the UH-1H VSTOLAND variable stability helicopter, the VFA-2 camera-and-terrain-board simulator ...
Aiken, Edwin W. +3 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
QUALITY CHARACTERISTICS OF BUFFALO CHEEK MEAT [PDF]
A study was undertaken to determine the physicochemical and microbiological qualities of fresh buffalo cheek meat. The results of this study characterise buffalo cheek meat as having relatively higher pH and lower TBA no. and cooking loss.
V. N. Vasudevan, V. Venkataramanujam
doaj
Pilot evaluation of sailplane handling qualities [PDF]
The evaluation sailplanes were found generally deficient in the area of cockpit layout. The pilots indicated general dissatisfaction with high pitch sensitivity especially when coupled with inertially induced stick forces.
Bennett, A. G., Jr.
core +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source

